Publikation:

Intracellular Conformations of Human Telomeric Quadruplexes Studied by Electron Paramagnetic Resonance Spectroscopy

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2012

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http://nbn-resolving.de/urn:nbn:de:bsz:352-206315
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https://doi.org/10.1002/cphc.201100980
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ChemPhysChem. 2012, 13(6), pp. 1444-1447. ISSN 1439-4235. eISSN 1439-7641. Available under: doi: 10.1002/cphc.201100980

Zusammenfassung

In-cell DEER (in-cell double electron electron resonance) is applied to investigate quadruplex formation of the human telomeric repeat d[AGGG(TTAGGG)(3)]. The initially unfolded DNA sequence forms a mixture of different quadruplex topologies upon injection into living cells. In addition, time-dependent distance measurements are carried out to monitor quadruplex folding.

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540 Chemie

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ISO 690AZARKH, Mykhailo, Vijay SINGH, Oliver OKLE, Daniel R. DIETRICH, Jörg S. HARTIG, Malte DRESCHER, 2012. Intracellular Conformations of Human Telomeric Quadruplexes Studied by Electron Paramagnetic Resonance Spectroscopy. In: ChemPhysChem. 2012, 13(6), pp. 1444-1447. ISSN 1439-4235. eISSN 1439-7641. Available under: doi: 10.1002/cphc.201100980
BibTex
@article{Azarkh2012-04-23Intra-20631,
  year={2012},
  doi={10.1002/cphc.201100980},
  title={Intracellular Conformations of Human Telomeric Quadruplexes Studied by Electron Paramagnetic Resonance Spectroscopy},
  number={6},
  volume={13},
  issn={1439-4235},
  journal={ChemPhysChem},
  pages={1444--1447},
  author={Azarkh, Mykhailo and Singh, Vijay and Okle, Oliver and Dietrich, Daniel R. and Hartig, Jörg S. and Drescher, Malte}
}
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