Publikation:

MHC class II DRB diversity, selection pattern and population structure in a neotropical bat species, Noctilio albiventris.

Lade...
Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2011

Autor:innen

Schad, Julia
Voigt, Christian C
Sommer, Simone

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Heredity. 2011, 107(2), pp. 115-126. ISSN 0018-067X. eISSN 1365-2540. Available under: doi: 10.1038/hdy.2010.173

Zusammenfassung

Genes of the major histocompatibility complex (MHC) play a crucial role in the immune response of vertebrates, alter the individual odour and are involved in shaping mating preferences. Pathogen-mediated selection, sexual selection and maternal-fetal interactions have been proposed as the main drivers of frequently observed high levels of polymorphism in functionally important parts of the MHC. Bats constitute the second largest mammalian order and have recently emerged as important vectors of infectious diseases. In addition, Chiroptera are interesting study subjects in evolutionary ecology in the context of olfactory communication, mate choice and associated fitness benefits. Thus, it is surprising that they belong to the least studied mammalian taxa in terms of their MHC diversity. In this study, we investigated the variability in the functionally important MHC class II gene DRB, selection pattern and population structure in the group-living lesser bulldog bat, Noctilio albiventris in Panama. We found a single expressed, polymorphic Noal-DRB gene with clear evidence for positive selection. Roosting colonies were not genetically differentiated, but females showed lower levels of heterozygosity than males, which might be explained by female driven mechanisms of sexual selection. In addition, this study provides the pre-requisites for further investigations of the role of the individual MHC constitution in parasite resistance, olfactory communication and mate choice in N. albiventris and other bats.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Major histocompatibility complex polymorphism, positive selection, population structure, neotropical bat, Noctilio albiventris, Panama

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690SCHAD, Julia, Dina K. N. DECHMANN, Christian C VOIGT, Simone SOMMER, 2011. MHC class II DRB diversity, selection pattern and population structure in a neotropical bat species, Noctilio albiventris.. In: Heredity. 2011, 107(2), pp. 115-126. ISSN 0018-067X. eISSN 1365-2540. Available under: doi: 10.1038/hdy.2010.173
BibTex
@article{Schad2011-08class-17697,
  year={2011},
  doi={10.1038/hdy.2010.173},
  title={MHC class II DRB diversity, selection pattern and population structure in a neotropical bat species, Noctilio albiventris.},
  number={2},
  volume={107},
  issn={0018-067X},
  journal={Heredity},
  pages={115--126},
  author={Schad, Julia and Dechmann, Dina K. N. and Voigt, Christian C and Sommer, Simone}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/17697">
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/17697"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Schad, Julia</dc:contributor>
    <dcterms:issued>2011-08</dcterms:issued>
    <dcterms:title>MHC class II DRB diversity, selection pattern and population structure in a neotropical bat species, Noctilio albiventris.</dcterms:title>
    <dc:contributor>Voigt, Christian C</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-02-01T11:06:13Z</dc:date>
    <dc:contributor>Dechmann, Dina K. N.</dc:contributor>
    <dc:creator>Sommer, Simone</dc:creator>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Dechmann, Dina K. N.</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-02-01T11:06:13Z</dcterms:available>
    <dcterms:abstract xml:lang="eng">Genes of the major histocompatibility complex (MHC) play a crucial role in the immune response of vertebrates, alter the individual odour and are involved in shaping mating preferences. Pathogen-mediated selection, sexual selection and maternal-fetal interactions have been proposed as the main drivers of frequently observed high levels of polymorphism in functionally important parts of the MHC. Bats constitute the second largest mammalian order and have recently emerged as important vectors of infectious diseases. In addition, Chiroptera are interesting study subjects in evolutionary ecology in the context of olfactory communication, mate choice and associated fitness benefits. Thus, it is surprising that they belong to the least studied mammalian taxa in terms of their MHC diversity. In this study, we investigated the variability in the functionally important MHC class II gene DRB, selection pattern and population structure in the group-living lesser bulldog bat, Noctilio albiventris in Panama. We found a single expressed, polymorphic Noal-DRB gene with clear evidence for positive selection. Roosting colonies were not genetically differentiated, but females showed lower levels of heterozygosity than males, which might be explained by female driven mechanisms of sexual selection. In addition, this study provides the pre-requisites for further investigations of the role of the individual MHC constitution in parasite resistance, olfactory communication and mate choice in N. albiventris and other bats.</dcterms:abstract>
    <dc:creator>Schad, Julia</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Sommer, Simone</dc:contributor>
    <dc:creator>Voigt, Christian C</dc:creator>
    <dcterms:bibliographicCitation>Publ. in: Heredity ; 107 (2011), 2. - S. 115-126</dcterms:bibliographicCitation>
    <dc:language>eng</dc:language>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen