Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV

Gritsch, Philipp; Stempel, Erik; Gaich, Tanja

Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2013

Autor:innen

Gritsch, Philipp

Stempel, Erik

Gaich, Tanja

DOI (zitierfähiger Link)

https://doi.org/10.1021/ol4026217

Sammlungen

Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Organic Letters. 2013, 15(21), pp. 5472-5475. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol4026217

Zusammenfassung

An enantioselective gram-scale synthesis of one of the most potent SIRT1-inhibitors has been accomplished by an unprecedented domino reaction sequence establishing the cyclohepta[b]indole core. This method was developed for application in natural product synthesis of a variety of indole alkaloids.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

GRITSCH, Philipp, Erik STEMPEL, Tanja GAICH, 2013. Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV. In: Organic Letters. 2013, 15(21), pp. 5472-5475. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol4026217

BibTex

@article{Gritsch2013-11Enant-38333,
  year={2013},
  doi={10.1021/ol4026217},
  title={Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV},
  number={21},
  volume={15},
  issn={1523-7060},
  journal={Organic Letters},
  pages={5472--5475},
  author={Gritsch, Philipp and Stempel, Erik and Gaich, Tanja}
}

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