Transient functional blood flow change in the human brain measured noninvasively by diffusing-wave spectroscopy

Li, Jun; Ninck, Markus; Koban, Leonie; Elbert, Thomas; Kissler, Johanna; Gisler, Thomas

Transient functional blood flow change in the human brain measured noninvasively by diffusing-wave spectroscopy

Dateien

jlimnincketal.pdfGröße: 690.12 KBDownloads: 352

Datum

2009

Autor:innen

Koban, Leonie

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Physik
Psychologie
Zukunftskolleg

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Optics letters. 2009, 33(19), pp. 2233-2235. ISSN 0146-9592. eISSN 1539-4794. Available under: doi: 10.1364/OL.33.002233

Zusammenfassung

Multispeckle diffusing-wave spectroscopy (DWS) is used to measure blood flow transients in the human visual cortex following stimulation by 7.5 Hz full-field and checkerboard flickering. The average decay time τd characterizing the decay of the DWS autocorrelation function shows a biphasic behavior; within about 2 s after stimulation onset, τd increases rapidly to about 6% above the baseline value. At later times, τd slowly decreases and reaches a steady-state value about 5% below the baseline value after about 15 s. The initial increase of the DWS signal suggests a transient reduction of the cortical blood flow velocity shortly after stimulation onset. Measurements of this transient response at different positions over the primary visual cortex show a spatial pattern different from the one measured by electroencephalography.

Fachgebiet (DDC)

530 Physik

Schlagwörter

Blutfluß, Gehirn, nicht invasive Messung, blood flow change, diffusing-wave spectroscopy, brain

Zitieren

ISO 690

LI, Jun, Markus NINCK, Leonie KOBAN, Thomas ELBERT, Johanna KISSLER, Thomas GISLER, 2009. Transient functional blood flow change in the human brain measured noninvasively by diffusing-wave spectroscopy. In: Optics letters. 2009, 33(19), pp. 2233-2235. ISSN 0146-9592. eISSN 1539-4794. Available under: doi: 10.1364/OL.33.002233

BibTex

@article{Li2009Trans-9509,
  year={2009},
  doi={10.1364/OL.33.002233},
  title={Transient functional blood flow change in the human brain measured noninvasively by diffusing-wave spectroscopy},
  number={19},
  volume={33},
  issn={0146-9592},
  journal={Optics letters},
  pages={2233--2235},
  author={Li, Jun and Ninck, Markus and Koban, Leonie and Elbert, Thomas and Kissler, Johanna and Gisler, Thomas}
}

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