KOPS - The Institutional Repository of the University of Konstanz

Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass

Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass

Type of Publication: Journal article
URI (citable link): http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-128200
Author: Marx, Andreas; Summerer, Daniel
Year of publication: 2002
Published in: ChemBioChem ; 3 (2002), 5. - pp. 405-407. - ISSN 1439-4227. - eISSN 1439-7633
DOI (citable link): https://dx.doi.org/10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4
Summary:
New DNA polymerase structures that differ significantly from known high-fidelity DNA polymerases provide new insights into how polymerases bypass damaged DNA like 1. Crystal structures of several Y-family DNA polymerases have recently been solved (see right-hand picture) and suggest that more open active sites may be the reason for the error propensity of low-fidelity polymerases.
Subject (DDC): 540 Chemistry
Keywords: DNA damage, DNA polymerases, DNA replication, thymidine dimers, UV light
Link to License: In Copyright

Cite This

Files in this item

[PDF]
Name: marxsummerer.pdf
Size: 817 KiB
Format: PDF
View/Open
Checksum: MD5:c4c014398faba0255323565b69b7b72a

MARX, Andreas, Daniel SUMMERER, 2002. Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass. In: ChemBioChem. 3(5), pp. 405-407. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4

@article{Marx2002Molec-9607, title={Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass}, year={2002}, doi={10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4}, number={5}, volume={3}, issn={1439-4227}, journal={ChemBioChem}, pages={405--407}, author={Marx, Andreas and Summerer, Daniel} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/9607"> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:issued>2002</dcterms:issued> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:creator>Marx, Andreas</dc:creator> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/9607/1/marxsummerer.pdf"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/9607/1/marxsummerer.pdf"/> <dc:rights>terms-of-use</dc:rights> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:title>Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass</dcterms:title> <dc:format>application/pdf</dc:format> <dc:contributor>Marx, Andreas</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:13:06Z</dc:date> <dc:language>eng</dc:language> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/9607"/> <dcterms:bibliographicCitation>First publ. in: ChemBioChem 3 (2002), 5, pp. 405-407</dcterms:bibliographicCitation> <dc:creator>Summerer, Daniel</dc:creator> <dc:contributor>Summerer, Daniel</dc:contributor> <dcterms:abstract xml:lang="eng">New DNA polymerase structures that differ significantly from known high-fidelity DNA polymerases provide new insights into how polymerases bypass damaged DNA like 1. Crystal structures of several Y-family DNA polymerases have recently been solved (see right-hand picture) and suggest that more open active sites may be the reason for the error propensity of low-fidelity polymerases.</dcterms:abstract> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:13:06Z</dcterms:available> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> </rdf:Description> </rdf:RDF>

Downloads since Oct 1, 2014 (Information about access statistics)

marxsummerer.pdf 474

This item appears in the following Collection(s)

Search KOPS


Browse

My Account