Increased erythropoietin production after myocardial infarction in mice

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MENGOZZI, M., Renato LATINI, M. SALIO, Alessandra SFACTERIA, G. PIEDIMONTE, Jens GAMMELTOFT GERWIEN, Marcel LEIST, Anna-Leena SIRÉN, Pietro GHEZZI, Simona CHIMENTI, 2006. Increased erythropoietin production after myocardial infarction in mice. In: Heart. 92(6), pp. 838-839. ISSN 1355-6037. eISSN 1468-201X. Available under: doi: 10.1136/hrt.2005.064105

@article{Mengozzi2006Incre-8719, title={Increased erythropoietin production after myocardial infarction in mice}, year={2006}, doi={10.1136/hrt.2005.064105}, number={6}, volume={92}, issn={1355-6037}, journal={Heart}, pages={838--839}, author={Mengozzi, M. and Latini, Renato and Salio, M. and Sfacteria, Alessandra and Piedimonte, G. and Gammeltoft Gerwien, Jens and Leist, Marcel and Sirén, Anna-Leena and Ghezzi, Pietro and Chimenti, Simona} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dc:creator>Ghezzi, Pietro</dc:creator> <dc:creator>Chimenti, Simona</dc:creator> <dspace:hasBitstream rdf:resource=""/> <dc:contributor>Mengozzi, M.</dc:contributor> <dc:date rdf:datatype="">2011-03-24T17:45:56Z</dc:date> <dspace:isPartOfCollection rdf:resource=""/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:issued>2006</dcterms:issued> <dc:rights>terms-of-use</dc:rights> <dc:contributor>Gammeltoft Gerwien, Jens</dc:contributor> <dc:creator>Gammeltoft Gerwien, Jens</dc:creator> <dcterms:rights rdf:resource=""/> <dcterms:hasPart rdf:resource=""/> <dcterms:abstract xml:lang="eng">In addition to its role as the main regulator of erythropoiesis, erythropoietin has a wide range of protective, antiapoptotic activities in vitro and in vivo, particularly in the brain and, as more recently shown, in the heart.1 Of note, erythropoietin is not exclusively produced by fetal liver and adult kidney but is expressed also in the brain, where it can be induced by hypoxia or ischaemia. Several studies underline the potential role of erythropoietin in mediating hypoxic ischaemic preconditioning in the brain. On the other hand, the heart has never been described as a site for erythropoietin production. However, hypoxia inducible factor 1 (HIF-1), the main transcriptional regulator of erythropoietin, is induced by hypoxia in myocardial cells in vivo and in vitro. HIF-1 has recently been reported to mediate hypoxic preconditioning in the heart. We investigated whether, as in the brain, erythropoietin is produced in mouse ischaemic heart.</dcterms:abstract> <dcterms:title>Increased erythropoietin production after myocardial infarction in mice</dcterms:title> <dc:creator>Leist, Marcel</dc:creator> <dc:creator>Salio, M.</dc:creator> <dc:format>application/pdf</dc:format> <bibo:uri rdf:resource=""/> <dc:contributor>Piedimonte, G.</dc:contributor> <dc:creator>Piedimonte, G.</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Latini, Renato</dc:contributor> <dc:creator>Sfacteria, Alessandra</dc:creator> <dcterms:bibliographicCitation>First publ. in: Heart 92 (2006), 6, pp. 838-839</dcterms:bibliographicCitation> <dc:contributor>Sirén, Anna-Leena</dc:contributor> <dc:creator>Mengozzi, M.</dc:creator> <dc:contributor>Chimenti, Simona</dc:contributor> <dc:contributor>Sfacteria, Alessandra</dc:contributor> <dc:contributor>Ghezzi, Pietro</dc:contributor> <dcterms:isPartOf rdf:resource=""/> <dc:contributor>Salio, M.</dc:contributor> <dc:contributor>Leist, Marcel</dc:contributor> <dc:creator>Sirén, Anna-Leena</dc:creator> <dcterms:available rdf:datatype="">2011-03-24T17:45:56Z</dcterms:available> <dc:language>eng</dc:language> <dc:creator>Latini, Renato</dc:creator> </rdf:Description> </rdf:RDF>

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