Involvement of protons in the ion transport cycle of Na+ ,K+-ATPase

Cite This

Files in this item

Checksum: MD5:7fdfdf9a9c643a5bcbcb440a902265fb

GRISHANIN, Kirill O., V. Yu. TASHKIN, Alexander A. LENZ, Hans-Jürgen APELL, Valerij S. SOKOLOV, 2010. Involvement of protons in the ion transport cycle of Na+ ,K+-ATPase. In: Biochemistry (Moscow) : Supplement Series A). 4(4), pp. 397-402. ISSN 1990-7478. eISSN 1990-7494. Available under: doi: 10.1134/S1990747810040100

@article{Grishanin2010Invol-8369, title={Involvement of protons in the ion transport cycle of Na+ ,K+-ATPase}, year={2010}, doi={10.1134/S1990747810040100}, number={4}, volume={4}, issn={1990-7478}, journal={Biochemistry (Moscow) : Supplement Series A)}, pages={397--402}, author={Grishanin, Kirill O. and Tashkin, V. Yu. and Lenz, Alexander A. and Apell, Hans-Jürgen and Sokolov, Valerij S.} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dc:creator>Grishanin, Kirill O.</dc:creator> <dc:contributor>Lenz, Alexander A.</dc:contributor> <dc:contributor>Grishanin, Kirill O.</dc:contributor> <dspace:hasBitstream rdf:resource=""/> <dc:creator>Lenz, Alexander A.</dc:creator> <dc:language>eng</dc:language> <dcterms:hasPart rdf:resource=""/> <dcterms:issued>2010</dcterms:issued> <dc:rights>terms-of-use</dc:rights> <dc:date rdf:datatype="">2011-03-24T17:43:01Z</dc:date> <dcterms:isPartOf rdf:resource=""/> <dspace:isPartOfCollection rdf:resource=""/> <dcterms:rights rdf:resource=""/> <dc:creator>Tashkin, V. Yu.</dc:creator> <dc:format>application/pdf</dc:format> <dcterms:bibliographicCitation>Publ. in: Biochemistry (Moscow) : Supplement Series A ; 4 (2010), 4. - pp. 397-402</dcterms:bibliographicCitation> <dc:creator>Sokolov, Valerij S.</dc:creator> <dcterms:title>Involvement of protons in the ion transport cycle of Na+ ,K+-ATPase</dcterms:title> <dc:contributor>Apell, Hans-Jürgen</dc:contributor> <dc:contributor>Sokolov, Valerij S.</dc:contributor> <dc:contributor>Tashkin, V. Yu.</dc:contributor> <bibo:uri rdf:resource=""/> <dcterms:abstract xml:lang="eng">The effect of pH on electrogenic sodium transport by the Na+,K+-ATPase has been studied. Experiments were carried out by admittance recording in a model system consisting of a bilayer lipid membrane with adsorbed membrane fragments containing purified Na+,K+-ATPase. Changes in the membrane admittance (capacitance and conductance increments in response to photo-induced release of ATP from caged ATP) were measured as function of AC voltage frequency, sodium ion concentration, and pH. In solutions containing 150 mM Na+, the frequency dependence of capacitance increments was not significantly dependent on pH in the range between 6 and 8. At a low NaCl concentration (3 mM), the capacitance increments at low frequencies decreased with the increasing pH. In the absence of NaCl, the frequency-dependent capacitance increment at low frequencies was similar to that measured in the presence of 3 mM NaCl. These results may be explained by involvement of protons in the Na+,K+-ATPase pump cycle, i.e., electroneutral exchange of sodium ions for protons under physiological conditions, electrogenic transport of sodium ions at high pH, and electrogenic transport of protons at low concentrations (and in the absence) of sodium ions.</dcterms:abstract> <dcterms:available rdf:datatype="">2011-05-31T22:25:04Z</dcterms:available> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Apell, Hans-Jürgen</dc:creator> </rdf:Description> </rdf:RDF>

Downloads since Oct 1, 2014 (Information about access statistics)

12779.pdf 190

This item appears in the following Collection(s)

Search KOPS


My Account