KOPS - Das Institutionelle Repositorium der Universität Konstanz

Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment

Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:6ab11daba90c601eb4943a86b66bcfef

AULOCK, Sonja von, Siegfried MORATH, Lars HARENG, Sylvia KNAPP, Kok P. M. van KESSEL, Jos A. G. van STRIJP, Thomas HARTUNG, 2003. Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment. In: Immunobiology. 208(4), pp. 413-422. ISSN 0171-2985

@article{Aulock2003Lipot-8196, title={Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment}, year={2003}, doi={10.1078/0171-2985-00285}, number={4}, volume={208}, issn={0171-2985}, journal={Immunobiology}, pages={413--422}, author={Aulock, Sonja von and Morath, Siegfried and Hareng, Lars and Knapp, Sylvia and Kessel, Kok P. M. van and Strijp, Jos A. G. van and Hartung, Thomas} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/8196"> <dcterms:issued>2003</dcterms:issued> <dc:format>application/pdf</dc:format> <dc:creator>Hareng, Lars</dc:creator> <dc:contributor>Aulock, Sonja von</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:41:20Z</dcterms:available> <dc:contributor>Knapp, Sylvia</dc:contributor> <dc:creator>Morath, Siegfried</dc:creator> <dc:creator>Aulock, Sonja von</dc:creator> <dc:language>eng</dc:language> <dc:contributor>Strijp, Jos A. G. van</dc:contributor> <dc:creator>Hartung, Thomas</dc:creator> <dc:contributor>Morath, Siegfried</dc:contributor> <dc:contributor>Hareng, Lars</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:41:20Z</dc:date> <dcterms:bibliographicCitation>First publ. in: Immunobiology 208 (2003), 4, pp. 413-422</dcterms:bibliographicCitation> <dc:creator>Strijp, Jos A. G. van</dc:creator> <dc:contributor>Kessel, Kok P. M. van</dc:contributor> <dc:creator>Kessel, Kok P. M. van</dc:creator> <dcterms:rights rdf:resource="https://creativecommons.org/licenses/by-nc-nd/2.0/legalcode"/> <dc:rights>deposit-license</dc:rights> <dcterms:abstract xml:lang="eng">Lipoteichoic acid (LTA) is a major immunostimulatory principle of Gram-positive bacteria. Intranasal application of LTA from S. aureus to mice resulted in greatly increased neutrophil and macrophage counts in the bronchoalveolar lavage as well as increased levels of the chemokine KC. The potential of highly pure, bioactive LTA from S. aureus to induce neutrophil recruitment and activation was investigated further in the human system.Although neutrophils expressed the key known receptors, CD14, TLR2 and TLR6, LTA did not induce or prime neutrophils for oxidative burst, or release of chemokines, bactericidal permeability-increasing protein or myeloperoxidase. However, LTA induced a strong release of the chemoattractants LTB4, IL-8, C5a, MCP-1 and the colony-stimulating factor G-CSF in whole blood comparable to stimulation with the same concentration of LPS (S. abortus equi). Further, the cytokine and chemoattractant pattern induced by LTA correlated well with that induced by live S. aureus of the same strain.LTA does not appear to activate neutrophils directly, but is a strong stimulus for the recruitment of phagocytes to the site of infection.</dcterms:abstract> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/8196"/> <dc:contributor>Hartung, Thomas</dc:contributor> <dc:creator>Knapp, Sylvia</dc:creator> <dcterms:title>Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment</dcterms:title> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

2003AulockImmunobiol.PDF 133

Das Dokument erscheint in:

deposit-license Solange nicht anders angezeigt, wird die Lizenz wie folgt beschrieben: deposit-license

KOPS Suche


Stöbern

Mein Benutzerkonto