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Membrane Trafficking in Protozoa : SNARE Proteins, H+-ATPase, Actin, and Other Key Players in Ciliates

Membrane Trafficking in Protozoa : SNARE Proteins, H+-ATPase, Actin, and Other Key Players in Ciliates

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Prüfsumme: MD5:8e05d36799707defaf55946a97419597

PLATTNER, Helmut, 2010. Membrane Trafficking in Protozoa : SNARE Proteins, H+-ATPase, Actin, and Other Key Players in Ciliates. In: International Review of Cell and Molecular Biology. 280, pp. 79-184

@article{Plattner2010Membr-7710, title={Membrane Trafficking in Protozoa : SNARE Proteins, H+-ATPase, Actin, and Other Key Players in Ciliates}, year={2010}, doi={10.1016/S1937-6448(10)80003-6}, volume={280}, journal={International Review of Cell and Molecular Biology}, pages={79--184}, author={Plattner, Helmut} }

Plattner, Helmut deposit-license 2011-03-24T17:36:33Z 2011-03-24T17:36:33Z First publ. in: International Review of Cell and Molecular Biology 280 (2010), pp. 79-184 Due to their well-defined pathways of vesicle trafficking and manyfold mutants ciliates have served as good model systems. Further studies required the development of databases, now available for Paramecium and Tetrahymena. A variety of key players have been identified and characterized based on BLAST search, domain analysis, localization, and gene-silencing studies. They include NSF (N-ethylmaleimide sensitive factor), SNAREs (soluble NSF attachment protein [SNAP] receptors), the H<sup>+</sup>-ATPase (V-ATPase) and actin, while Arf (ADP-ribosylation factor) and Rab-type small GTPases, COPs (coatamer proteins) and many others remain to be elucidated. The number of SNAREs, H<sup>+</sup>-ATPase subunits, and actins ever found within one cell type are unexpectedly high and most of the manifold vesicle types seem to be endowed with specific molecular components pertinent to trafficking. As in higher eukaryotes, multifactorial targeting likely occurs. It appears that, in parallel to higher organisms, ciliates have evolved a similar structural and molecular complexity of vesicle trafficking. application/pdf 2010 Plattner, Helmut eng Membrane Trafficking in Protozoa : SNARE Proteins, H+-ATPase, Actin, and Other Key Players in Ciliates

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

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