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Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish

Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish

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GIBERT, Yann, D. Randy MCMILLAN, Kathleen KAYES-WANDOVER, Axel MEYER, Gerrit BEGEMANN, Perrin C. WHITE, 2005. Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish. In: Gene. 353(2), pp. 200-206. ISSN 0378-1119. Available under: doi: 10.1016/j.gene.2005.05.015

@article{Gibert2005Analy-7692, title={Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish}, year={2005}, doi={10.1016/j.gene.2005.05.015}, number={2}, volume={353}, issn={0378-1119}, journal={Gene}, pages={200--206}, author={Gibert, Yann and McMillan, D. Randy and Kayes-Wandover, Kathleen and Meyer, Axel and Begemann, Gerrit and White, Perrin C.} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/7692"> <dc:contributor>Gibert, Yann</dc:contributor> <dcterms:title>Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish</dcterms:title> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <dc:language>eng</dc:language> <dc:creator>Begemann, Gerrit</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:36:26Z</dcterms:available> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7692"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Meyer, Axel</dc:contributor> <dc:creator>Meyer, Axel</dc:creator> <dc:contributor>White, Perrin C.</dc:contributor> <dc:creator>White, Perrin C.</dc:creator> <dcterms:bibliographicCitation>First publ. in: Gene 353 (2005), pp. 200 206</dcterms:bibliographicCitation> <dcterms:rights rdf:resource="https://creativecommons.org/licenses/by-nc-nd/2.0/legalcode"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <dcterms:abstract xml:lang="eng">Very Large G-protein coupled Receptor-1 (VLGR1/Mass1/USH2C) is the largest known cell surface protein in vertebrates. Mutations in VLGR1 are associated with audiogenic epilepsy in mice and Usher syndrome (sensorineural deafness and retinitis pigmentosa) in humans. We characterized the zebrafish VLGR1 gene (vlgr1). It is 51% identical to human VLGR1 in amino acid sequence, but is 64% identical in the 7-transmembrane and cytoplasmic domains. It is 6199 amino acids in size and is encoded by a 19.2 kb mRNA. All introns correspond in location and phase to those of the human and mouse genes. In situ hybridization studies of zebrafish embryos demonstrate vlgr1 expression in the developing central nervous system, particularly in the hypothalamus, epiphysis and in the rhombic lips. Expression in the eye is associated with the optic nerve. Further studies using zebrafish may help ascertain the role of Vlgr1 in neural development.</dcterms:abstract> <dc:creator>McMillan, D. Randy</dc:creator> <dc:contributor>McMillan, D. Randy</dc:contributor> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7692/1/analysis_of_the_very_large_g_protein_coupled_receptor_gene_in_zebrafish.pdf"/> <dc:creator>Kayes-Wandover, Kathleen</dc:creator> <dcterms:issued>2005</dcterms:issued> <dc:contributor>Begemann, Gerrit</dc:contributor> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7692/1/analysis_of_the_very_large_g_protein_coupled_receptor_gene_in_zebrafish.pdf"/> <dc:creator>Gibert, Yann</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:36:26Z</dc:date> <dc:format>application/pdf</dc:format> <dc:contributor>Kayes-Wandover, Kathleen</dc:contributor> <dc:rights>terms-of-use</dc:rights> </rdf:Description> </rdf:RDF>

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