@article{Bastmeyer1994Simil-7350,
  year={1994},
  doi={10.1002/glia.440110403},
  title={Similarities and differences between fish oligodendrocytes and schwann cells in vitro},
  number={4},
  volume={11},
  issn={0894-1491},
  journal={Glia},
  pages={300--314},
  author={Bastmeyer, Martin and Jeserich, Gunnar and Stürmer, Claudia}
}

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    <dcterms:issued>1994</dcterms:issued>
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    <dcterms:title>Similarities and differences between fish oligodendrocytes and schwann cells in vitro</dcterms:title>
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    <dc:creator>Stürmer, Claudia</dc:creator>
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    <dcterms:abstract xml:lang="eng">n light of the striking differences between oligodendrocytes of the optic nerve/tract of adult goldfish and their mammalian counterparts, a further characterization of goldfish oligodendrocytes was performed. A comparison with Schwann cells was included because fish optic nerve/tract-derived oligodendrocytes bear remarkable similarities to this type of glial cell. Fish optic nerve/tract-derived oligodendrocytes that had differentiated into 04 and 6D2-positive cells and thus expressed early myelin marker molecules were found to incorporate BrdU and to divide in vitro over a period of weeks. For the induction of more advanced markers of myelinogenesis such as the CNS-specific myelin protein 36K, oligodendrocytes required extensive contact with axons. Other agents, such as fetal calf or carp serum, substrate components, or forscolin failed, however, to induce 36K expression. 04/6D2-positive oligodendrocytes could be distinguished from fish 6D2-positive Schwann cells derived from cranial nerves by their antigenic pheno-type: Schwann cells but not oligodendrocytes exhibited the low affinity NGF receptor. While both cell types carry the cell adhesion molecules NCAM, E 587 antigen, and the L2/HNK-1 epitope, only Schwann cells possess a further adhesion molecule, Neurolin.</dcterms:abstract>
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    <dc:contributor>Bastmeyer, Martin</dc:contributor>
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    <dc:creator>Bastmeyer, Martin</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:33:43Z</dc:date>
    <dcterms:bibliographicCitation>First publ. in: Glia 11 (1994), pp. 300-314</dcterms:bibliographicCitation>
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    <dc:contributor>Jeserich, Gunnar</dc:contributor>
    <dc:creator>Jeserich, Gunnar</dc:creator>
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