'Small' talk : Opa proteins as mediators of Neisseria-host-cell communication
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| Type of Publication: | Journal article |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-41571 |
| Author: | Hauck, Christof R.; Meyer, Thomas F. |
| Year of publication: | 2003 |
| Published in: | Current Opinion in Microbiology ; 6 (2003), 1. - pp. 43-49. - ISSN 1369-5274 |
| DOI (citable link): | https://dx.doi.org/10.1016/S1369-5274(03)00004-3 |
| Summary: |
Opa proteins are variable outer membrane proteins of Neisseria gonorrhoeae and Neisseria meningitidis that mediate tight interaction of these pathogens with human cells. They have emerged as a paradigm of a bacterial toolbox allowing recognition of different host receptors and orchestrating the cell type tropism displayed by pathogenic Neisseriae. Recent work has highlighted the molecular basis of Opa-protein-host-receptor interaction and has shed new light on the functional consequences of this interaction with regard to bacterial attachment, invasion, and responses elicited in particular host cells.
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| Subject (DDC): | 570 Biosciences, Biology |
| Link to License: | Attribution-NonCommercial-NoDerivs 2.0 Generic |
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HAUCK, Christof R., Thomas F. MEYER, 2003. 'Small' talk : Opa proteins as mediators of Neisseria-host-cell communication. In: Current Opinion in Microbiology. 6(1), pp. 43-49. ISSN 1369-5274. Available under: doi: 10.1016/S1369-5274(03)00004-3
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