PrPc and reggies/flotillins are contained in and released via lipid-rich vesicles in Jurkat T cells

Lade...
Vorschaubild
Dateien
Zu diesem Dokument gibt es keine Dateien.
Datum
2004
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Cellular and Molecular Life Sciences. 2004, 61(16), pp. 2092-2099. ISSN 1420-682X. eISSN 1420-9071. Available under: doi: 10.1007/s00018-004-4193-x
Zusammenfassung

A new model of caveolin association with lipid body cores has recently been proposed which may be relevant to a number of cellular processes, e.g. lipid body generation. Here we show that PrPc and reggie-1 and reggie-2 also occur in the cores of Nile Red/Bodipy-stained (neutral lipid-containing) vesicular structures and, in immunoblots, in the lipid-enriched fraction after density gradient centrifugation. These lipid-rich vesicles increase in number following cell feeding with oleic acid, differ from early endosome antigen 1- and Lamp-2-positive endosomes/lysosomes, exhibit an opaque content and lack surrounding actin staining. Our results suggest that the content of these vesicles, together with reggie-1 and -2 and PrPc, is expelled.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Cellular prion protein, reggie/flotillin, lipid-rich vesicle, release/exocytosis
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690REUTER, Alexander, Ulrike BINKLE, Claudia STÜRMER, Helmut PLATTNER, 2004. PrPc and reggies/flotillins are contained in and released via lipid-rich vesicles in Jurkat T cells. In: Cellular and Molecular Life Sciences. 2004, 61(16), pp. 2092-2099. ISSN 1420-682X. eISSN 1420-9071. Available under: doi: 10.1007/s00018-004-4193-x
BibTex
@article{Reuter2004reggi-7056,
  year={2004},
  doi={10.1007/s00018-004-4193-x},
  title={PrPc and reggies/flotillins are contained in and released via lipid-rich vesicles in Jurkat T cells},
  number={16},
  volume={61},
  issn={1420-682X},
  journal={Cellular and Molecular Life Sciences},
  pages={2092--2099},
  author={Reuter, Alexander and Binkle, Ulrike and Stürmer, Claudia and Plattner, Helmut}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/7056">
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:31:10Z</dcterms:available>
    <dcterms:issued>2004</dcterms:issued>
    <dc:creator>Plattner, Helmut</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7056"/>
    <dc:creator>Reuter, Alexander</dc:creator>
    <dc:contributor>Reuter, Alexander</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7056/1/107_PrPc_and_Reggie_Flotillins.pdf"/>
    <dcterms:title>PrPc and reggies/flotillins are contained in and released via lipid-rich vesicles in Jurkat T cells</dcterms:title>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:31:10Z</dc:date>
    <dc:contributor>Stürmer, Claudia</dc:contributor>
    <dc:contributor>Binkle, Ulrike</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:abstract xml:lang="eng">A new model of caveolin association with lipid body cores has recently been proposed which may be relevant to a number of cellular processes, e.g. lipid body generation. Here we show that PrPc and reggie-1 and reggie-2 also occur in the cores of Nile Red/Bodipy-stained (neutral lipid-containing) vesicular structures and, in immunoblots, in the lipid-enriched fraction after density gradient centrifugation. These lipid-rich vesicles increase in number following cell feeding with oleic acid, differ from early endosome antigen 1- and Lamp-2-positive endosomes/lysosomes, exhibit an opaque content and lack surrounding actin staining. Our results suggest that the content of these vesicles, together with reggie-1 and -2 and PrPc, is expelled.</dcterms:abstract>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Plattner, Helmut</dc:contributor>
    <dc:creator>Binkle, Ulrike</dc:creator>
    <dc:creator>Stürmer, Claudia</dc:creator>
    <dcterms:bibliographicCitation>First publ. in: Cellular and Molecular Life Sciences 61 (2004), pp. 2092-2099</dcterms:bibliographicCitation>
    <dc:format>application/pdf</dc:format>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:language>eng</dc:language>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7056/1/107_PrPc_and_Reggie_Flotillins.pdf"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen