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Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P.

Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P.

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DAUBERSCHMIDT, Carole, Daniel R. DIETRICH, Christian SCHLATTER, 1997. Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P.. In: Aquatic toxicology. 37(4), pp. 283-294. ISSN 0166-445X. eISSN 1879-1514

@article{Dauberschmidt1997Inves-6721, title={Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P.}, year={1997}, number={4}, volume={37}, issn={0166-445X}, journal={Aquatic toxicology}, pages={283--294}, author={Dauberschmidt, Carole and Dietrich, Daniel R. and Schlatter, Christian} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/6721"> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6721"/> <dc:language>eng</dc:language> <dcterms:bibliographicCitation>First publ. in: Aquatic toxicology 37 (1997), 4, pp. 283-294</dcterms:bibliographicCitation> <dc:contributor>Schlatter, Christian</dc:contributor> <dc:contributor>Dauberschmidt, Carole</dc:contributor> <dc:creator>Dietrich, Daniel R.</dc:creator> <dcterms:issued>1997</dcterms:issued> <dcterms:rights rdf:resource="https://creativecommons.org/licenses/by-nc-nd/2.0/legalcode"/> <dcterms:title>Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P.</dcterms:title> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:41Z</dc:date> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:41Z</dcterms:available> <dc:contributor>Dietrich, Daniel R.</dc:contributor> <dc:creator>Schlatter, Christian</dc:creator> <dcterms:abstract xml:lang="eng">Microsomes of Dreissena polymorpha were able to biotransform the organophosphates thiometon and disulfoton significantly after 1 h incubation at 10 °C. Contrarily to vertebrates, biotransformation with mussel microsomes occurred without the addition of reduction equivalents (NADPH), at a considerably lower extent however. Metabolites of thiometon and disulfoton were detected with gas chromatography/mass spectrometry (GC/MS) analysis. The P450 content of whole mussel tissue was 8 pmol mg−1 protein being two orders of magnitude lower than the amounts measured in mammal liver. Ethoxycoumarin deethylase (ECOD) activity could be measured at 10 °C in microsomes of Dreissena (22 pmol min−1 mg−1 protein) but not at 37 °C. ECOD activity was inhibited in the presence of NADPH (measured activity 3 pmol min−1 mg−1).</dcterms:abstract> <dc:format>application/pdf</dc:format> <dc:creator>Dauberschmidt, Carole</dc:creator> <dc:rights>deposit-license</dc:rights> </rdf:Description> </rdf:RDF>

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