KOPS - Das Institutionelle Repositorium der Universität Konstanz

Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury

Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:13cb07a2516c5c8ab80ab2fd937160bd

ERTEL, Wolfgang, Marius KEEL, Reto STOCKER, Hans-Georg IMHOF, Marcel LEIST, Ursula STECKHOLZER, Masako TANAKA, Otmar TRENTZ, Shigekazu NAGATA, 1997. Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury. In: Journal of Neuroimmunology. 80(1/2), pp. 93-96. ISSN 0165-5728

@article{Ertel1997Detec-6706, title={Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury}, year={1997}, doi={10.1016/S0165-5728(97)00139-2}, number={1/2}, volume={80}, issn={0165-5728}, journal={Journal of Neuroimmunology}, pages={93--96}, author={Ertel, Wolfgang and Keel, Marius and Stocker, Reto and Imhof, Hans-Georg and Leist, Marcel and Steckholzer, Ursula and Tanaka, Masako and Trentz, Otmar and Nagata, Shigekazu} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/6706"> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:33Z</dc:date> <dc:contributor>Leist, Marcel</dc:contributor> <dc:creator>Ertel, Wolfgang</dc:creator> <dc:creator>Stocker, Reto</dc:creator> <dc:contributor>Nagata, Shigekazu</dc:contributor> <dc:creator>Keel, Marius</dc:creator> <dc:creator>Nagata, Shigekazu</dc:creator> <dcterms:issued>1997</dcterms:issued> <dc:contributor>Trentz, Otmar</dc:contributor> <dc:creator>Steckholzer, Ursula</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:33Z</dcterms:available> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> <dc:format>application/pdf</dc:format> <dc:contributor>Stocker, Reto</dc:contributor> <dc:creator>Leist, Marcel</dc:creator> <dc:language>eng</dc:language> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6706"/> <dc:contributor>Tanaka, Masako</dc:contributor> <dc:contributor>Steckholzer, Ursula</dc:contributor> <dc:rights>deposit-license</dc:rights> <dc:creator>Tanaka, Masako</dc:creator> <dcterms:abstract xml:lang="eng">When the cell surface molecule Fas is triggered by its agonist Fas ligand the result is apoptosis of these cells and tissue destruction. To elucidate the pathophysiological relevance of Fas ligand in patients with cerebral oedema caused by trauma, we examined its concentrations in cerebrospinal fluid in 18 patients using specific ELISA. Serum and cerebrospinal fluid from healthy people and injured patients without head trauma did not contain detectable Fas ligand. In contrast, cerebrospinal fluid from patients with severe brain injury contained high concentrations of Fas ligand without detectable concentrations in serum. Soluble Fas ligand concentrations in cerebrospinal fluid correlated significantly with severity of brain injury. The Fas-Fas ligand-system may have a pivotal role in causing oedema and local tissue destruction in the brain after severe head injury.</dcterms:abstract> <dc:contributor>Imhof, Hans-Georg</dc:contributor> <dc:creator>Imhof, Hans-Georg</dc:creator> <dcterms:bibliographicCitation>First publ. in: Journal of Neuroimmunology 80 (1997), 1/2, pp. 93-96</dcterms:bibliographicCitation> <dc:contributor>Ertel, Wolfgang</dc:contributor> <dcterms:title>Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury</dcterms:title> <dc:creator>Trentz, Otmar</dc:creator> <dc:contributor>Keel, Marius</dc:contributor> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

Ertel_W_J_Neuroimmunol_1997.pdf 755

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto