KOPS - Das Institutionelle Repositorium der Universität Konstanz

Three-dimensional structure of the nonaheme cytochrome c from desulfovibrio Desulfuricans essex in the Fe(III) state at 1.89 Å resolution

Three-dimensional structure of the nonaheme cytochrome c from desulfovibrio Desulfuricans essex in the Fe(III) state at 1.89 Å resolution

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:8df295668f7820352820ba46ca0e68ad

UMHAU, Stephan, Günter FRITZ, Kay DIEDERICHS, Jason BREED, Wolfram WELTE, Peter M. KRONECK, 2001. Three-dimensional structure of the nonaheme cytochrome c from desulfovibrio Desulfuricans essex in the Fe(III) state at 1.89 Å resolution. In: Biochemistry. 40(5), pp. 1308-1316. ISSN 0006-2960. eISSN 1520-4995

@article{Umhau2001Three-6684, title={Three-dimensional structure of the nonaheme cytochrome c from desulfovibrio Desulfuricans essex in the Fe(III) state at 1.89 Å resolution}, year={2001}, doi={10.1021/bi001479a}, number={5}, volume={40}, issn={0006-2960}, journal={Biochemistry}, pages={1308--1316}, author={Umhau, Stephan and Fritz, Günter and Diederichs, Kay and Breed, Jason and Welte, Wolfram and Kroneck, Peter M.} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/6684"> <dc:format>application/pdf</dc:format> <dc:contributor>Kroneck, Peter M.</dc:contributor> <dc:language>eng</dc:language> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> <dc:contributor>Fritz, Günter</dc:contributor> <dc:creator>Breed, Jason</dc:creator> <dc:creator>Umhau, Stephan</dc:creator> <dcterms:abstract xml:lang="eng">A nine heme group containing cytochrome c isolated from the soluble and membrane fractions of Desulfovibrio desulfuricans Essex, termed nonaheme cytochrome c, was crystallized, and the structure was solved using the multiple wavelength anomalous dispersion (MAD) phasing method. Refinement was carried out to a resolution of 1.89 Å, and anisotropic temperature factors were addressed to the iron and sulfur atoms in the model. The structure revealed two cytochrome c3 like domains with the typical arrangement of four heme centers. Both domains flanked an extra heme buried under the protein surface. This heme is held in position by loop extensions in each of the two domains. Although both the N- and C-terminal tetraheme domains exhibit a fold and heme arrangement very similar to that of cytochrome c3, they differ considerably in their loop extensions and electrostatic surface. Analysis of the structure provides evidence for a different function of both domains, namely, anchoring the protein in a transmembranous complex with the N-terminal domain and formation of an electron-transfer complex with hydrogenase by the C-terminal domain.</dcterms:abstract> <dc:creator>Fritz, Günter</dc:creator> <dc:contributor>Breed, Jason</dc:contributor> <dcterms:title>Three-dimensional structure of the nonaheme cytochrome c from desulfovibrio Desulfuricans essex in the Fe(III) state at 1.89 Å resolution</dcterms:title> <dc:rights>deposit-license</dc:rights> <dc:contributor>Welte, Wolfram</dc:contributor> <dc:creator>Kroneck, Peter M.</dc:creator> <dc:contributor>Umhau, Stephan</dc:contributor> <dc:creator>Diederichs, Kay</dc:creator> <dc:creator>Welte, Wolfram</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:20Z</dc:date> <dc:contributor>Diederichs, Kay</dc:contributor> <dcterms:issued>2001</dcterms:issued> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6684"/> <dcterms:bibliographicCitation>First publ. in: Biochemistry ; 40 (2001). - S. 1308-1316</dcterms:bibliographicCitation> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

Three_dimensional_structure_of_the_nonaheme_cytochrome_c_from_desulfovibrio_desulfuricans_essex_in_the_Fe.pdf 102

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto