Visual recognition of social signals by a tectothalamic neural circuit

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KAPPEL, Johannes M., Dominique FÖRSTER, Katja SLANGEWAL, Inbal SHAINER, Fabian SVARA, Joseph C. DONOVAN, Shachar SHERMAN, Michał JANUSZEWSKI, Herwig BAIER, Johannes LARSCH, 2022. Visual recognition of social signals by a tectothalamic neural circuit. In: Nature. Springer Nature. 608(7921), pp. 146-152. ISSN 0028-0836. eISSN 1476-4687. Available under: doi: 10.1038/s41586-022-04925-5

@article{Kappel2022-08-04Visua-58206, title={Visual recognition of social signals by a tectothalamic neural circuit}, year={2022}, doi={10.1038/s41586-022-04925-5}, number={7921}, volume={608}, issn={0028-0836}, journal={Nature}, pages={146--152}, author={Kappel, Johannes M. and Förster, Dominique and Slangewal, Katja and Shainer, Inbal and Svara, Fabian and Donovan, Joseph C. and Sherman, Shachar and Januszewski, Michał and Baier, Herwig and Larsch, Johannes} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dspace:hasBitstream rdf:resource=""/> <dc:creator>Shainer, Inbal</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Januszewski, Michał</dc:creator> <dc:contributor>Baier, Herwig</dc:contributor> <dcterms:issued>2022-08-04</dcterms:issued> <dc:contributor>Januszewski, Michał</dc:contributor> <dc:creator>Larsch, Johannes</dc:creator> <bibo:uri rdf:resource=""/> <dc:creator>Svara, Fabian</dc:creator> <dc:creator>Slangewal, Katja</dc:creator> <dc:creator>Baier, Herwig</dc:creator> <dc:creator>Sherman, Shachar</dc:creator> <dc:date rdf:datatype="">2022-07-29T06:45:19Z</dc:date> <dcterms:available rdf:datatype="">2022-07-29T06:45:19Z</dcterms:available> <dcterms:rights rdf:resource=""/> <dspace:isPartOfCollection rdf:resource=""/> <dc:rights>Attribution 4.0 International</dc:rights> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Förster, Dominique</dc:creator> <dc:contributor>Kappel, Johannes M.</dc:contributor> <dc:contributor>Svara, Fabian</dc:contributor> <dcterms:abstract xml:lang="eng">Social affiliation emerges from individual-level behavioural rules that are driven by conspecific signals1,2,3,4,5. Long-distance attraction and short-distance repulsion, for example, are rules that jointly set a preferred interanimal distance in swarms6,7,8. However, little is known about their perceptual mechanisms and executive neural circuits3. Here we trace the neuronal response to self-like biological motion9,10, a visual trigger for affiliation in developing zebrafish2,11. Unbiased activity mapping and targeted volumetric two-photon calcium imaging revealed 21 activity hotspots distributed throughout the brain as well as clustered biological-motion-tuned neurons in a multimodal, socially activated nucleus of the dorsal thalamus. Individual dorsal thalamus neurons encode local acceleration of visual stimuli mimicking typical fish kinetics but are insensitive to global or continuous motion. Electron microscopic reconstruction of dorsal thalamus neurons revealed synaptic input from the optic tectum and projections into hypothalamic areas with conserved social function12,13,14. Ablation of the optic tectum or dorsal thalamus selectively disrupted social attraction without affecting short-distance repulsion. This tectothalamic pathway thus serves visual recognition of conspecifics, and dissociates neuronal control of attraction from repulsion during social affiliation, revealing a circuit underpinning collective behaviour.</dcterms:abstract> <dcterms:title>Visual recognition of social signals by a tectothalamic neural circuit</dcterms:title> <dc:creator>Donovan, Joseph C.</dc:creator> <dc:contributor>Donovan, Joseph C.</dc:contributor> <dc:contributor>Shainer, Inbal</dc:contributor> <dcterms:isPartOf rdf:resource=""/> <dc:creator>Kappel, Johannes M.</dc:creator> <dc:contributor>Förster, Dominique</dc:contributor> <dc:contributor>Larsch, Johannes</dc:contributor> <dcterms:isPartOf rdf:resource=""/> <dc:contributor>Slangewal, Katja</dc:contributor> <dc:contributor>Sherman, Shachar</dc:contributor> <dc:language>eng</dc:language> <dspace:isPartOfCollection rdf:resource=""/> <dcterms:hasPart rdf:resource=""/> </rdf:Description> </rdf:RDF>

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