Recent advances in cancer immunotherapy

Lade...
Vorschaubild
Dateien
Sun_2-15vis3cdtrm3r2.pdf
Sun_2-15vis3cdtrm3r2.pdfGröße: 862.2 KBDownloads: 118
Datum
2021
Autor:innen
Sun, Qiang
Melino, Gerry
Jiang, Jingting
Wang, Ying
Shi, Yufang
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Link zur Lizenz
EU-Projektnummer
DFG-Projektnummer
Projekt
Open Access-Veröffentlichung
Sammlungen
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Discover Oncology. Springer New York. 2021, 12(1), 27. ISSN 1868-8497. eISSN 1868-8500. Available under: doi: 10.1007/s12672-021-00422-9
Zusammenfassung

Cancer immunotherapy represents a major advance in the cure of cancer following the dramatic advancements in the development and refinement of chemotherapies and radiotherapies. In the recent decades, together with the development of early diagnostic techniques, immunotherapy has significantly contributed to improving the survival of cancer patients. The immune-checkpoint blockade agents have been proven effective in a significant fraction of standard therapy refractory patients. Importantly, recent advances are providing alternative immunotherapeutic tools that could help overcome their limitations. In this mini review, we provide an overview on the main steps of the discovery of classic immune-checkpoint blockade agents and summarise the most recent development of novel immunotherapeutic strategies, such as tumour antigens, bispecific antibodies and TCR-engineered T cells.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Cancer immunotherapy, Immune check point blockade, T cell receptor, Cancer survival, p53, KRas
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690SUN, Qiang, Gerry MELINO, Ivano AMELIO, Jingting JIANG, Ying WANG, Yufang SHI, 2021. Recent advances in cancer immunotherapy. In: Discover Oncology. Springer New York. 2021, 12(1), 27. ISSN 1868-8497. eISSN 1868-8500. Available under: doi: 10.1007/s12672-021-00422-9
BibTex
@article{Sun2021-12Recen-56461,
  year={2021},
  doi={10.1007/s12672-021-00422-9},
  title={Recent advances in cancer immunotherapy},
  number={1},
  volume={12},
  issn={1868-8497},
  journal={Discover Oncology},
  author={Sun, Qiang and Melino, Gerry and Amelio, Ivano and Jiang, Jingting and Wang, Ying and Shi, Yufang},
  note={Article Number: 27}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/56461">
    <dc:contributor>Shi, Yufang</dc:contributor>
    <dcterms:abstract xml:lang="eng">Cancer immunotherapy represents a major advance in the cure of cancer following the dramatic advancements in the development and refinement of chemotherapies and radiotherapies. In the recent decades, together with the development of early diagnostic techniques, immunotherapy has significantly contributed to improving the survival of cancer patients. The immune-checkpoint blockade agents have been proven effective in a significant fraction of standard therapy refractory patients. Importantly, recent advances are providing alternative immunotherapeutic tools that could help overcome their limitations. In this mini review, we provide an overview on the main steps of the discovery of classic immune-checkpoint blockade agents and summarise the most recent development of novel immunotherapeutic strategies, such as tumour antigens, bispecific antibodies and TCR-engineered T cells.</dcterms:abstract>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/56461"/>
    <dc:creator>Wang, Ying</dc:creator>
    <dcterms:issued>2021-12</dcterms:issued>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56461/1/Sun_2-15vis3cdtrm3r2.pdf"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Sun, Qiang</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Melino, Gerry</dc:creator>
    <dc:creator>Amelio, Ivano</dc:creator>
    <dc:language>eng</dc:language>
    <dc:creator>Jiang, Jingting</dc:creator>
    <dc:contributor>Jiang, Jingting</dc:contributor>
    <dcterms:title>Recent advances in cancer immunotherapy</dcterms:title>
    <dc:contributor>Melino, Gerry</dc:contributor>
    <dc:contributor>Wang, Ying</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-02-09T10:31:59Z</dc:date>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56461/1/Sun_2-15vis3cdtrm3r2.pdf"/>
    <dc:contributor>Amelio, Ivano</dc:contributor>
    <dc:contributor>Sun, Qiang</dc:contributor>
    <dc:creator>Shi, Yufang</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-02-09T10:31:59Z</dcterms:available>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Unbekannt