Extracellular Movement of Signaling Molecules

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Mueller_2-13atztwdnd01u8.pdf(968 KB)
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2011
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Schier, Alexander F.
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urn:nbn:de:bsz:352-2-13atztwdnd01u8
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10.1016/j.devcel.2011.06.001
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Developmental Cell ; 21 (2011), 1. - pp. 145-158. - Cell Press. - ISSN 1534-5807. - eISSN 1878-1551
Abstract
Extracellular signaling molecules have crucial roles in development and homeostasis, and their incorrect deployment can lead to developmental defects and disease states. Signaling molecules are released from sending cells, travel to target cells, and act over length scales of several orders of magnitude, from morphogen-mediated patterning of small developmental fields to hormonal signaling throughout the organism. We discuss how signals are modified and assembled for transport, which routes they take to reach their targets, and how their range is affected by mobility and stability.
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570 Biosciences, Biology
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ISO 690MÜLLER, Patrick, Alexander F. SCHIER, 2011. Extracellular Movement of Signaling Molecules. In: Developmental Cell. Cell Press. 21(1), pp. 145-158. ISSN 1534-5807. eISSN 1878-1551. Available under: doi: 10.1016/j.devcel.2011.06.001
BibTex
@article{Muller2011-07-19Extra-55593,
  year={2011},
  doi={10.1016/j.devcel.2011.06.001},
  title={Extracellular Movement of Signaling Molecules},
  number={1},
  volume={21},
  issn={1534-5807},
  journal={Developmental Cell},
  pages={145--158},
  author={Müller, Patrick and Schier, Alexander F.}
}
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