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Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression

Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression

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BLECHERT, Oliver, Desiree DOUGLAS, Stefan BAUMGARTNER, 2011. Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression. In: Insect Molecular Biology. Wiley-Blackwell. 20(2), pp. 257-265. eISSN 0962-1075. Available under: doi: 10.1111/j.1365-2583.2010.01063.x

@article{Blechert2011-04Conse-50999, title={Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression}, year={2011}, doi={10.1111/j.1365-2583.2010.01063.x}, number={2}, volume={20}, journal={Insect Molecular Biology}, pages={257--265}, author={Blechert, Oliver and Douglas, Desiree and Baumgartner, Stefan} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/50999"> <dc:creator>Baumgartner, Stefan</dc:creator> <dc:contributor>Douglas, Desiree</dc:contributor> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:title>Conserved function of the Krüppel gap gene in the blowfly Lucilia sericata, despite anterior shift of expression</dcterms:title> <dc:creator>Blechert, Oliver</dc:creator> <dc:rights>terms-of-use</dc:rights> <dcterms:issued>2011-04</dcterms:issued> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/50999"/> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-09-23T15:31:25Z</dc:date> <dc:contributor>Blechert, Oliver</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-09-23T15:31:25Z</dcterms:available> <dc:language>eng</dc:language> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Baumgartner, Stefan</dc:contributor> <dc:creator>Douglas, Desiree</dc:creator> <dcterms:abstract xml:lang="eng">To determine whether expression patterns of segmentation genes found in Drosophila melanogaster can be scaled to pattern larger insects, we studied the expression of the Krüppel (Kr) gene in the blowfly Lucilia sericata. Compared with Drosophila Kr, L. sericata Kr showed an unexpected 10% shift of expression towards the anterior pole. Furthermore, expression domains not found in D. melanogaster were present at the blastoderm stage of L. sericata. To compare Kr activity and function, we employed RNA interference‐mediated gene silencing. We found Kr phenotypes in L. sericata comparable with those observed in D. melanogaster, demonstrating that L. sericata Kr functions as a gap gene as it does in Drosophila. Our results show that, despite an anterior shift in expression, Kr function has remained conserved during the evolution of the blowflies.</dcterms:abstract> </rdf:Description> </rdf:RDF>

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