Systematic synthesis and characterization of a series of different bromoalkylglycosides by Fischer glycosylation
| Type of Publication: | Journal article |
| Publication status: | Published |
| Author: | Williams, Lara; Schunck, Natalie; Götz, Kathrin H.; Ringwald, Markus; Schmidt, Magnus S. |
| Year of publication: | 2019 |
| Published in: | Carbohydrate research ; 486 (2019). - 107841. - ISSN 0008-6215. - eISSN 1873-426X |
| Pubmed ID: | 31655420 |
| DOI (citable link): | https://dx.doi.org/10.1016/j.carres.2019.107841 |
| Summary: |
In order to investigate the possibilities of Fischer glycosylation towards the synthesis of bromoalkylglycosides we performed a variety of different reactions resulting in a small library of 16 different glycosides. Using standardized reaction conditions we could gain a broad range of results from small to higher yields. Finally we randomly selected three reactions and performed them with higher amounts of bromoalcohol resulting in significantly better yields, showing the optimization potential of these basic research work.
|
| Subject (DDC): | 540 Chemistry |
| Keywords: | Carbohydrates, Fischer glycosylation, Glycosides, Bromides, Linker |
| Bibliography of Konstanz: | Yes |
| Refereed: | Unknown |
Cite This
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||
WILLIAMS, Lara, Natalie SCHUNCK, Kathrin H. GÖTZ, Markus RINGWALD, Magnus S. SCHMIDT, 2019. Systematic synthesis and characterization of a series of different bromoalkylglycosides by Fischer glycosylation. In: Carbohydrate research. 486, 107841. ISSN 0008-6215. eISSN 1873-426X. Available under: doi: 10.1016/j.carres.2019.107841
@article{Williams2019-12-01Syste-47874, title={Systematic synthesis and characterization of a series of different bromoalkylglycosides by Fischer glycosylation}, year={2019}, doi={10.1016/j.carres.2019.107841}, volume={486}, issn={0008-6215}, journal={Carbohydrate research}, author={Williams, Lara and Schunck, Natalie and Götz, Kathrin H. and Ringwald, Markus and Schmidt, Magnus S.}, note={Article Number: 107841} }
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/47874"> <dc:creator>Williams, Lara</dc:creator> <dc:contributor>Ringwald, Markus</dc:contributor> <dc:creator>Götz, Kathrin H.</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:contributor>Schunck, Natalie</dc:contributor> <dc:contributor>Schmidt, Magnus S.</dc:contributor> <dcterms:abstract xml:lang="eng">In order to investigate the possibilities of Fischer glycosylation towards the synthesis of bromoalkylglycosides we performed a variety of different reactions resulting in a small library of 16 different glycosides. Using standardized reaction conditions we could gain a broad range of results from small to higher yields. Finally we randomly selected three reactions and performed them with higher amounts of bromoalcohol resulting in significantly better yields, showing the optimization potential of these basic research work.</dcterms:abstract> <dc:creator>Schmidt, Magnus S.</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-12-06T14:07:06Z</dc:date> <dc:contributor>Götz, Kathrin H.</dc:contributor> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:creator>Schunck, Natalie</dc:creator> <dc:contributor>Williams, Lara</dc:contributor> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/47874"/> <dc:language>eng</dc:language> <dcterms:title>Systematic synthesis and characterization of a series of different bromoalkylglycosides by Fischer glycosylation</dcterms:title> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-12-06T14:07:06Z</dcterms:available> <dcterms:issued>2019-12-01</dcterms:issued> <dc:creator>Ringwald, Markus</dc:creator> </rdf:Description> </rdf:RDF>
This item appears in the following Collection(s)
Search KOPS
Browse
My Account
