Expanding the Genetic Code for Site-Directed Spin-Labeling

Cite This

Files in this item

Checksum: MD5:fce30d42397d681fe2c2aeab824d4fae

BRAUN, Theresa, Malte DRESCHER, Daniel SUMMERER, 2019. Expanding the Genetic Code for Site-Directed Spin-Labeling. In: International journal of molecular sciences. 20(2), 373. eISSN 1422-0067. Available under: doi: 10.3390/ijms20020373

@article{Braun2019-01-16Expan-45319, title={Expanding the Genetic Code for Site-Directed Spin-Labeling}, year={2019}, doi={10.3390/ijms20020373}, number={2}, volume={20}, journal={International journal of molecular sciences}, author={Braun, Theresa and Drescher, Malte and Summerer, Daniel}, note={Article Number: 373} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/45319"> <dcterms:issued>2019-01-16</dcterms:issued> <dc:creator>Braun, Theresa</dc:creator> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:contributor>Drescher, Malte</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-03-05T14:46:27Z</dc:date> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/45319/3/Drescher_2-3ahh6n4nc9ro7.pdf"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:rights>terms-of-use</dc:rights> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:abstract xml:lang="eng">Site-directed spin labeling (SDSL) in combination with electron paramagnetic resonance (EPR) spectroscopy enables studies of the structure, dynamics, and interactions of proteins in the noncrystalline state. The scope and analytical value of SDSL⁻EPR experiments crucially depends on the employed labeling strategy, with key aspects being labeling chemoselectivity and biocompatibility, as well as stability and spectroscopic properties of the resulting label. The use of genetically encoded noncanonical amino acids (ncAA) is an emerging strategy for SDSL that holds great promise for providing excellent chemoselectivity and potential for experiments in complex biological environments such as living cells. We here give a focused overview of recent advancements in this field and discuss their potentials and challenges for advancing SDSL⁻EPR studies.</dcterms:abstract> <dc:creator>Summerer, Daniel</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-03-05T14:46:27Z</dcterms:available> <dcterms:title>Expanding the Genetic Code for Site-Directed Spin-Labeling</dcterms:title> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Braun, Theresa</dc:contributor> <dc:language>eng</dc:language> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/45319/3/Drescher_2-3ahh6n4nc9ro7.pdf"/> <dc:creator>Drescher, Malte</dc:creator> <dcterms:rights rdf:resource="https://kops.uni-konstanz.de/page/termsofuse"/> <dc:contributor>Summerer, Daniel</dc:contributor> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/45319"/> </rdf:Description> </rdf:RDF>

Downloads since Mar 5, 2019 (Information about access statistics)

Drescher_2-3ahh6n4nc9ro7.pdf 33

This item appears in the following Collection(s)

Search KOPS


Browse

My Account