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Type of Publication: | Journal article |
Publication status: | Published |
URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-ajcqic3gx0zy3 |
Author: | Mier, Walter; Mier, Daniela |
Year of publication: | 2015 |
Published in: | Frontiers in human neuroscience ; 9 (2015). - 249. - eISSN 1662-5161 |
Pubmed ID: | 26042013 |
DOI (citable link): | https://dx.doi.org/10.3389/fnhum.2015.00249 |
Summary: |
As neuronal pathologies cause only minor morphological alterations, molecular imaging techniques are a prerequisite for the study of diseases of the brain. The development of molecular probes that specifically bind biochemical markers and the advances of instrumentation have revolutionized the possibilities to gain insight into the human brain organization and beyond this-visualize structure-function and brain-behavior relationships. The review describes the development and current applications of functional brain imaging techniques with a focus on applications in psychiatry. A historical overview of the development of functional imaging is followed by the portrayal of the principles and applications of positron emission tomography (PET) and functional magnetic resonance imaging (fMRI), two key molecular imaging techniques that have revolutionized the ability to image molecular processes in the brain. We conclude that the juxtaposition of PET and fMRI in hybrid PET/MRI scanners enhances the significance of both modalities for research in neurology and psychiatry and might pave the way for a new area of personalized medicine.
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Subject (DDC): | 150 Psychology |
Keywords: | positron emission tomography, molecular imaging, radiotracers, neurological diseases, functional magnetic imaging |
Link to License: | Attribution 4.0 International |
Refereed: | Yes |
MIER, Walter, Daniela MIER, 2015. Advantages in functional imaging of the brain. In: Frontiers in human neuroscience. 9, 249. eISSN 1662-5161. Available under: doi: 10.3389/fnhum.2015.00249
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