KOPS - The Institutional Repository of the University of Konstanz

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

Cite This

Files in this item

Checksum: MD5:59c92dcaa77dc917911b17c83271ed87

ZHU, Yan, Tobias CZAUDERNA, Jinxin ZHAO, Matthias KLAPPERSTUECK, Mohd Hafidz Mahamad MAIFIAH, Mei-Ling HAN, Jing LU, Björn SOMMER, Falk SCHREIBER, Jian LI, 2018. Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa. In: GigaScience. 7(4), giy018. eISSN 2047-217X. Available under: doi: 10.1093/gigascience/giy021

@article{Zhu2018Genom-42970, title={Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa}, year={2018}, doi={10.1093/gigascience/giy021}, number={4}, volume={7}, journal={GigaScience}, author={Zhu, Yan and Czauderna, Tobias and Zhao, Jinxin and Klapperstueck, Matthias and Maifiah, Mohd Hafidz Mahamad and Han, Mei-Ling and Lu, Jing and Sommer, Björn and Schreiber, Falk and Li, Jian}, note={Article Number: giy018} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/42970"> <dc:contributor>Maifiah, Mohd Hafidz Mahamad</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-08-06T10:42:16Z</dcterms:available> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/42970/3/Zhu_2-esm0xmgvxmn56.pdf"/> <dc:creator>Klapperstueck, Matthias</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Zhu, Yan</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/36"/> <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/42970"/> <dc:creator>Lu, Jing</dc:creator> <dc:creator>Han, Mei-Ling</dc:creator> <dcterms:title>Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa</dcterms:title> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/36"/> <dc:contributor>Sommer, Björn</dc:contributor> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/42970/3/Zhu_2-esm0xmgvxmn56.pdf"/> <dc:creator>Czauderna, Tobias</dc:creator> <dc:contributor>Klapperstueck, Matthias</dc:contributor> <dc:creator>Zhao, Jinxin</dc:creator> <dc:contributor>Czauderna, Tobias</dc:contributor> <dcterms:issued>2018</dcterms:issued> <dc:contributor>Schreiber, Falk</dc:contributor> <dc:creator>Sommer, Björn</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-08-06T10:42:16Z</dc:date> <dc:contributor>Lu, Jing</dc:contributor> <dc:language>eng</dc:language> <dc:creator>Schreiber, Falk</dc:creator> <dc:contributor>Li, Jian</dc:contributor> <dc:contributor>Zhu, Yan</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:abstract xml:lang="eng">Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients, and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibiotics, it is necessary to systematically understand how P. aeruginosa alters its metabolism in response to polymyxin treatment, thereby facilitating the development of effective therapies. To this end, a genome-scale metabolic model (GSMM) was used to analyze bacterial metabolic changes at the systems level.</dcterms:abstract> <dc:rights>Attribution 4.0 International</dc:rights> <dc:contributor>Han, Mei-Ling</dc:contributor> <dc:creator>Li, Jian</dc:creator> <dc:creator>Maifiah, Mohd Hafidz Mahamad</dc:creator> <dc:contributor>Zhao, Jinxin</dc:contributor> </rdf:Description> </rdf:RDF>

Downloads since Aug 6, 2018 (Information about access statistics)

Zhu_2-esm0xmgvxmn56.pdf 123

This item appears in the following Collection(s)

Attribution 4.0 International Except where otherwise noted, this item's license is described as Attribution 4.0 International

Search KOPS


Browse

My Account