KOPS - The Institutional Repository of the University of Konstanz

Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase

Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase

Cite This

Files in this item

Files Size Format View

There are no files associated with this item.

GARCIA, Pilar, Marco MARINO, Olga MAYANS, 2004. Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase. In: Acta crystallographica Section D : Biological Crystallography. 60(12 - 2), pp. 2336-2339. ISSN 0907-4449. eISSN 1399-0047. Available under: doi: 10.1107/S0907444904026873

@article{Garcia2004Cryst-42088, title={Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase}, year={2004}, doi={10.1107/S0907444904026873}, number={12 - 2}, volume={60}, issn={0907-4449}, journal={Acta crystallographica Section D : Biological Crystallography}, pages={2336--2339}, author={Garcia, Pilar and Marino, Marco and Mayans, Olga} }

Garcia, Pilar The coiled-coil domain of dystrophia myotonica protein kinase (DMPK) has been cloned, overexpressed, purified and crystallized. Two crystal forms have been obtained that belong to space groups P3 and P2<sub>(1)</sub>2<sub>(1)</sub>2<sub>(1)</sub> and diffract to 2.4 and 1.6 A resolution, respectively. Experimental phases were obtained by MAD from an SeMet derivative. The location of selenium sites used molecular-replacement phases obtained from search models lacking sequence similarity with the coiled-coil under study. Both crystal forms contain three polypeptide chains in the asymmetric unit. eng 2018-04-18T10:16:03Z Marino, Marco Marino, Marco 2018-04-18T10:16:03Z Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase Mayans, Olga Garcia, Pilar 2004 Mayans, Olga

This item appears in the following Collection(s)

Search KOPS


Browse

My Account