Aufgrund von Vorbereitungen auf eine neue Version von KOPS, können kommenden Montag und Dienstag keine Publikationen eingereicht werden. (Due to preparations for a new version of KOPS, no publications can be submitted next Monday and Tuesday.)
Type of Publication: | Journal article |
Publication status: | Published |
Author: | Malla, Ashok; de Bonneville, Marianne; Shah, Jai; Jordan, Gerald; Pruessner, Marita; Faridi, Kia; Rabinovitch, Mark; Iyer, Srividya N.; Joober, Ridha |
Year of publication: | 2018 |
Published in: | Early Intervention in Psychiatry ; 12 (2018), 4. - pp. 715-719. - ISSN 1751-7885. - eISSN 1751-7893 |
Pubmed ID: | 28613411 |
DOI (citable link): | https://dx.doi.org/10.1111/eip.12431 |
Summary: |
Aim
We explored 2-year outcomes in a sample of clinical high risk (CHR) patients who converted to psychosis despite receiving interventions. Methods Of 167 CHR patients, 18 had converted to psychosis and received treatment for their first episode of psychosis in an early intervention service over 2 years. Results Compared to patients admitted directly to the same early intervention service without having been identified as CHR prior to onset of psychosis, CHR converters were in remission for fewer months (M = 5 vs M = 10); were more likely to be prescribed more than 1 antipsychotic medication (90% vs 68%) and to receive clozapine treatment (38% vs 2%) over 2 years. Conclusions CHR patients who convert to psychosis may be inherently more resistant to comprehensive treatment and may have poorer outcomes. Conversion to psychosis from a state of CHR can be reduced to a rate of 10%–12% following interventions, yet outcomes for patients who convert despite such interventions remain unexplored. |
Subject (DDC): | 150 Psychology |
Bibliography of Konstanz: | Yes |
Refereed: | Yes |
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MALLA, Ashok, Marianne DE BONNEVILLE, Jai SHAH, Gerald JORDAN, Marita PRUESSNER, Kia FARIDI, Mark RABINOVITCH, Srividya N. IYER, Ridha JOOBER, 2018. Outcome in patients converting to psychosis following a treated clinical high risk state. In: Early Intervention in Psychiatry. 12(4), pp. 715-719. ISSN 1751-7885. eISSN 1751-7893. Available under: doi: 10.1111/eip.12431
@article{Malla2018-08Outco-41411, title={Outcome in patients converting to psychosis following a treated clinical high risk state}, year={2018}, doi={10.1111/eip.12431}, number={4}, volume={12}, issn={1751-7885}, journal={Early Intervention in Psychiatry}, pages={715--719}, author={Malla, Ashok and de Bonneville, Marianne and Shah, Jai and Jordan, Gerald and Pruessner, Marita and Faridi, Kia and Rabinovitch, Mark and Iyer, Srividya N. and Joober, Ridha} }