Aufgrund von Vorbereitungen auf eine neue Version von KOPS, können am Montag, 6.2. und Dienstag, 7.2. keine Publikationen eingereicht werden. (Due to preparations for a new version of KOPS, no publications can be submitted on Monday, Feb. 6 and Tuesday, Feb. 7.)
Type of Publication: | Journal article |
Publication status: | Published |
URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-emplm7zacqca1 |
Author: | Betz, Karin; Nilforoushan, Arman; Wyss, Laura A.; Diederichs, Kay; Sturla, Shana J.; Marx, Andreas |
Year of publication: | 2017 |
Published in: | Chemical Communications : ChemComm ; 53 (2017), 94. - pp. 12704-12707. - ISSN 1359-7345. - eISSN 1364-548X |
Pubmed ID: | 29136072 |
DOI (citable link): | https://dx.doi.org/10.1039/c7cc07173f |
Summary: |
The possibility to sequence cytotoxic O6-alkylG DNA adducts would greatly benefit research. Recently we reported a benzimidazole-derived nucleotide that is selectively incorporated opposite the damaged site by a mutated DNA polymerase. Here we provide the structural basis for this reaction which may spur future developments in DNA damage sequencing.
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Subject (DDC): | 540 Chemistry |
Link to License: | In Copyright |
Bibliography of Konstanz: | Yes |
BETZ, Karin, Arman NILFOROUSHAN, Laura A. WYSS, Kay DIEDERICHS, Shana J. STURLA, Andreas MARX, 2017. Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase. In: Chemical Communications : ChemComm. 53(94), pp. 12704-12707. ISSN 1359-7345. eISSN 1364-548X. Available under: doi: 10.1039/c7cc07173f
@article{Betz2017-11-23Struc-40878, title={Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase}, year={2017}, doi={10.1039/c7cc07173f}, number={94}, volume={53}, issn={1359-7345}, journal={Chemical Communications : ChemComm}, pages={12704--12707}, author={Betz, Karin and Nilforoushan, Arman and Wyss, Laura A. and Diederichs, Kay and Sturla, Shana J. and Marx, Andreas} }
Betz_2-emplm7zacqca1.pdf | 179 |