KOPS - Das Institutionelle Repositorium der Universität Konstanz

Lateralized Feeding Behavior is Associated with Asymmetrical Neuroanatomy and Lateralized Gene Expressions in the Brain in Scale-Eating Cichlid Fish

Lateralized Feeding Behavior is Associated with Asymmetrical Neuroanatomy and Lateralized Gene Expressions in the Brain in Scale-Eating Cichlid Fish

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:c6abb97b9e445a14497f6dc6b2176653

LEE, Hyuk Je, Ralf F. SCHNEIDER, Tereza MANOUSAKI, Ji Hyoun KANG, Etienne LEIN, Paolo FRANCHINI, Axel MEYER, 2017. Lateralized Feeding Behavior is Associated with Asymmetrical Neuroanatomy and Lateralized Gene Expressions in the Brain in Scale-Eating Cichlid Fish. In: Genome biology and evolution. 9(11), pp. 3122-3136. eISSN 1759-6653. Available under: doi: 10.1093/gbe/evx218

@article{Lee2017-10-24Later-40797, title={Lateralized Feeding Behavior is Associated with Asymmetrical Neuroanatomy and Lateralized Gene Expressions in the Brain in Scale-Eating Cichlid Fish}, year={2017}, doi={10.1093/gbe/evx218}, number={11}, volume={9}, journal={Genome biology and evolution}, pages={3122--3136}, author={Lee, Hyuk Je and Schneider, Ralf F. and Manousaki, Tereza and Kang, Ji Hyoun and Lein, Etienne and Franchini, Paolo and Meyer, Axel} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/40797"> <dc:creator>Schneider, Ralf F.</dc:creator> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-30T12:10:31Z</dcterms:available> <dc:contributor>Lee, Hyuk Je</dc:contributor> <dc:creator>Meyer, Axel</dc:creator> <dcterms:issued>2017-10-24</dcterms:issued> <dc:contributor>Lein, Etienne</dc:contributor> <dc:creator>Lein, Etienne</dc:creator> <dc:contributor>Meyer, Axel</dc:contributor> <dc:creator>Kang, Ji Hyoun</dc:creator> <dcterms:title>Lateralized Feeding Behavior is Associated with Asymmetrical Neuroanatomy and Lateralized Gene Expressions in the Brain in Scale-Eating Cichlid Fish</dcterms:title> <dc:creator>Lee, Hyuk Je</dc:creator> <dc:contributor>Manousaki, Tereza</dc:contributor> <dcterms:abstract xml:lang="eng">Lateralized behavior ('handedness') is unusual, but consistently found across diverse animal lineages, including humans. It is thought to reflect brain anatomical and/or functional asymmetries, but its neuro-molecular mechanisms remain largely unknown. Lake Tanganyika scale-eating cichlid fish, Perissodus microlepis show pronounced asymmetry in their jaw morphology as well as handedness in feeding behavior - feeding scales preferentially only from one or the other side of their victims. This makes them an ideal model in which to investigate potential laterality in neuroanatomy and transcription in the brain in relation to behavioral handedness. After determining behavioral handedness in P. microlepis (preferred attack side), we estimated the volume of the hemispheres of brain regions and captured their gene expression profiles. Our analyses revealed that the degree of behavioral handedness is mirrored at the level of neuroanatomical asymmetry, particularly in the tectum opticum. Transcriptome analyses showed that different brain regions (tectum opticum, telencephalon, hypothalamus and cerebellum) display distinct expression patterns, potentially reflecting their developmental interrelationships. For numerous genes in each brain region, their extent of expression differences between hemispheres was found to be correlated with the degree of behavioral lateralization. Interestingly, the tectum opticum and telencephalon showed divergent biases on the direction of up- or down-regulation of the laterality candidate genes (e.g., grm2 ) in the hemispheres, highlighting the connection of handedness with gene expression profiles and the different roles of these brain regions. Hence, handedness in predation behavior may be caused by asymmetric size of brain hemispheres and also by lateralized gene expressions in the brain.</dcterms:abstract> <dc:language>eng</dc:language> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/40797"/> <dc:contributor>Franchini, Paolo</dc:contributor> <dc:creator>Franchini, Paolo</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-30T12:10:31Z</dc:date> <dc:contributor>Kang, Ji Hyoun</dc:contributor> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/40797/1/Lee_2-1q2y9y0apdl1e9.pdf"/> <dc:contributor>Schneider, Ralf F.</dc:contributor> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/40797/1/Lee_2-1q2y9y0apdl1e9.pdf"/> <dc:creator>Manousaki, Tereza</dc:creator> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 30.11.2017 (Informationen über die Zugriffsstatistik)

Lee_2-1q2y9y0apdl1e9.pdf 49

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto