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Sex differences in cortical thickness in first-time DWI offenders : A preliminary MRI study

Sex differences in cortical thickness in first-time DWI offenders : A preliminary MRI study

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BROWN, Thomas G., Jens PRUESSNER, Martin LEPAGE, Jacques TREMBLAY, Louise NADEAU, Marie Claude OUIMET, Katarina DEDOVIC, Stephanie DIMITROFF, Queenie WONG, 2014. Sex differences in cortical thickness in first-time DWI offenders : A preliminary MRI study. 5th International Conference on Women's Issues in Transportation. Paris, 14. Apr 2014 - 16. Apr 2014. In: Women's Issues in Transportation : “Bridging the Gap” ; 5th International Conference − Paris 14-16 April 2014. 5th International Conference on Women's Issues in Transportation. Paris, 14. Apr 2014 - 16. Apr 2014. Paris, pp. 315-325. ISBN 978-2-8399-1535-9

@inproceedings{Brown2014diffe-38734, title={Sex differences in cortical thickness in first-time DWI offenders : A preliminary MRI study}, year={2014}, isbn={978-2-8399-1535-9}, address={Paris}, booktitle={Women's Issues in Transportation : “Bridging the Gap” ; 5th International Conference − Paris 14-16 April 2014}, pages={315--325}, author={Brown, Thomas G. and Pruessner, Jens and Lepage, Martin and Tremblay, Jacques and Nadeau, Louise and Ouimet, Marie Claude and Dedovic, Katarina and Dimitroff, Stephanie and Wong, Queenie} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/38734"> <dc:creator>Brown, Thomas G.</dc:creator> <dc:creator>Ouimet, Marie Claude</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-04T09:12:20Z</dcterms:available> <dc:creator>Dimitroff, Stephanie</dc:creator> <dc:contributor>Dimitroff, Stephanie</dc:contributor> <dc:creator>Lepage, Martin</dc:creator> <dc:creator>Pruessner, Jens</dc:creator> <dcterms:issued>2014</dcterms:issued> <dc:contributor>Pruessner, Jens</dc:contributor> <dc:creator>Tremblay, Jacques</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-04T09:12:20Z</dc:date> <dc:creator>Nadeau, Louise</dc:creator> <dc:contributor>Ouimet, Marie Claude</dc:contributor> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/38734"/> <dc:contributor>Brown, Thomas G.</dc:contributor> <dc:contributor>Lepage, Martin</dc:contributor> <dcterms:title>Sex differences in cortical thickness in first-time DWI offenders : A preliminary MRI study</dcterms:title> <dcterms:abstract xml:lang="eng">Driving while impaired by alcohol (DWI) is a persistent yet preventable public health problem. Recent evidence indicates an increasing number of females engaging in DWI behaviour and distinct sex-based trajectories, though sex-based analysis is infrequent in DWI research, especially with respect to the role of cognitive processes. The current study investigated associations between sex, cortical thickness analysis using high resolution Magnetic Resonance Imaging (MRI) and psychological functioning in DWI offenders. It was hypothesized that male offenders possess brain features consistent with impaired executive control, while female offenders show more signs of alcohol misuse and psychological dysfunction. 31 male and 16 female DWI offenders, and 31 male and 31 female non-DWI drivers were recruited. All subjects underwent T1 high resolution MRI scanning and cortical thickness analysis using the CIVET pipeline and assessment on sociodemographic, alcohol misuse, impulsivity, and psychological adjustment. Male DWI offenders, compared to male non-DWI comparators, showed reduced cortical thickness in the posterior and ventral anterior cingulate cortex, the parahippocampal gyrus and anterior insula, areas associated with decision making, error monitoring and emotional processing. Female DWI offenders, compared to their female non-DWI comparators, showed no signs of structural anomalies, but stronger signs of alcohol misuse and depression and anxiety-related dysfunction. These preliminary results suggest that sexual dimorphism contributes to the heterogeneity of the DWI offender population, the trajectory to DWI behaviour, and the uncertain effectiveness of generalized approaches to prevention.</dcterms:abstract> <dc:creator>Wong, Queenie</dc:creator> <dc:creator>Dedovic, Katarina</dc:creator> <dc:contributor>Dedovic, Katarina</dc:contributor> <dc:contributor>Tremblay, Jacques</dc:contributor> <dc:language>eng</dc:language> <dc:contributor>Nadeau, Louise</dc:contributor> <dc:contributor>Wong, Queenie</dc:contributor> </rdf:Description> </rdf:RDF>

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