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FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks

FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks

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ROHN, Hendrik, Anja HARTMANN, Astrid JUNKER, Björn H. JUNKER, Falk SCHREIBER, 2012. FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks. In: BMC Systems Biology. 6, 33. eISSN 1752-0509. Available under: doi: 10.1186/1752-0509-6-33

@article{Rohn2012FluxM-38504, title={FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks}, year={2012}, doi={10.1186/1752-0509-6-33}, volume={6}, journal={BMC Systems Biology}, author={Rohn, Hendrik and Hartmann, Anja and Junker, Astrid and Junker, Björn H. and Schreiber, Falk}, note={Article Number: 33} }

eng Junker, Björn H. Rohn, Hendrik Hartmann, Anja Hartmann, Anja 2017-04-18T12:37:11Z 2012 FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks Junker, Astrid Schreiber, Falk Background<br /><br />The quantification of metabolic fluxes is gaining increasing importance in the analysis of the metabolic behavior of biological systems such as organisms, tissues or cells. Various methodologies (wetlab or drylab) result in sets of fluxes which require an appropriate visualization for interpretation by scientists. The visualization of flux distributions is a necessary prerequisite for intuitive flux data exploration in the context of metabolic networks.<br /><br />Results<br /><br />We present FluxMap, a tool for the advanced visualization and exploration of flux data in the context of metabolic networks. The template-based flux data import assigns flux values and optional quality parameters (e. g. the confidence interval) to biochemical reactions. It supports the discrimination between mass and substance fluxes, such as C- or N-fluxes. After import, flux data mapping and network-based visualization allow the interactive exploration of the dataset. Various visualization options enable the user to adapt layout and network representation according to individual purposes.<br /><br />Conclusions<br /><br />The Vanted add-on FluxMap comprises a comprehensive set of functionalities for visualization and advanced visual exploration of flux distributions in biological networks. It is available as a Java open source tool from http://www.vanted.org/fluxmap. Junker, Astrid Junker, Björn H. Schreiber, Falk Rohn, Hendrik 2017-04-18T12:37:11Z

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