Molecular Modeling of P-Glycoprotein and Related Drugs

Zitieren

Dateien zu dieser Ressource

Dateien Größe Format Anzeige

Zu diesem Dokument gibt es keine Dateien.

PAJEVA, Ilza, Christoph GLOBISCH, Romy FLEISCHER, Ivanka TSAKOVSKA, Michael WIESE, 2005. Molecular Modeling of P-Glycoprotein and Related Drugs. In: Medicinal Chemistry Research. 14(2), pp. 106-117. ISSN 1054-2523. eISSN 1554-8120. Available under: doi: 10.1007/s00044-005-0127-x

@article{Pajeva2005-02Molec-38290, title={Molecular Modeling of P-Glycoprotein and Related Drugs}, year={2005}, doi={10.1007/s00044-005-0127-x}, number={2}, volume={14}, issn={1054-2523}, journal={Medicinal Chemistry Research}, pages={106--117}, author={Pajeva, Ilza and Globisch, Christoph and Fleischer, Romy and Tsakovska, Ivanka and Wiese, Michael} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/38290"> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:title>Molecular Modeling of P-Glycoprotein and Related Drugs</dcterms:title> <dc:contributor>Wiese, Michael</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-04T08:47:15Z</dc:date> <dc:creator>Globisch, Christoph</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:language>eng</dc:language> <dc:contributor>Fleischer, Romy</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Tsakovska, Ivanka</dc:contributor> <dcterms:issued>2005-02</dcterms:issued> <dc:creator>Pajeva, Ilza</dc:creator> <dc:contributor>Globisch, Christoph</dc:contributor> <dc:creator>Wiese, Michael</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-04T08:47:15Z</dcterms:available> <dc:contributor>Pajeva, Ilza</dc:contributor> <dcterms:abstract xml:lang="eng">This paper summarizes the results from molecular modeling of various multidrug resistance (MDR) modulators and the MDR protein P-glycoprotein (P-gp). Highly predictive 3D-QSAR models are obtained that can be used for anti-MDR activity prediction. The pharmacophore patterns of various drugs are identified. Models of P-gp are developed and a hypothesis for P-gp functioning is proposed.</dcterms:abstract> <dc:creator>Fleischer, Romy</dc:creator> <dc:creator>Tsakovska, Ivanka</dc:creator> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/38290"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> </rdf:Description> </rdf:RDF>

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto