KOPS - Das Institutionelle Repositorium der Universität Konstanz

Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis

Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:fdc5943abbe394d3ebdeb808fa95675b

BARBERON, Marie, Guillaume DUBEAUX, Cornelia KOLB, Erika ISONO, Enric ZELAZNY, Grégory VERT, 2014. Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis. In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 111(22), pp. 8293-8298. ISSN 0027-8424. eISSN 1091-6490. Available under: doi: 10.1073/pnas.1402262111

@article{Barberon2014-06-03Polar-38157, title={Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis}, year={2014}, doi={10.1073/pnas.1402262111}, number={22}, volume={111}, issn={0027-8424}, journal={Proceedings of the National Academy of Sciences of the United States of America (PNAS)}, pages={8293--8298}, author={Barberon, Marie and Dubeaux, Guillaume and Kolb, Cornelia and Isono, Erika and Zelazny, Enric and Vert, Grégory} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/38157"> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/38157/3/Barberon_0-398682.pdf"/> <dc:contributor>Zelazny, Enric</dc:contributor> <dc:creator>Isono, Erika</dc:creator> <dc:creator>Dubeaux, Guillaume</dc:creator> <dc:contributor>Dubeaux, Guillaume</dc:contributor> <dc:creator>Vert, Grégory</dc:creator> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <dcterms:abstract xml:lang="eng">In plants, the controlled absorption of soil nutrients by root epidermal cells is critical for growth and development. IRON-REGULATED TRANSPORTER 1 (IRT1) is the main root transporter taking up iron from the soil and is also the main entry route in plants for potentially toxic metals such as manganese, zinc, cobalt, and cadmium. Previous work demonstrated that the IRT1 protein localizes to early endosomes/trans-Golgi network (EE/TGN) and is constitutively endocytosed through a monoubiquitin- and clathrin-dependent mechanism. Here, we show that the availability of secondary non-iron metal substrates of IRT1 (Zn, Mn, and Co) controls the localization of IRT1 between the outer polar domain of the plasma membrane and EE/TGN in root epidermal cells. We also identify FYVE1, a phosphatidylinositol-3-phosphate-binding protein recruited to late endosomes, as an important regulator of IRT1-dependent metal transport and metal homeostasis in plants. FYVE1 controls IRT1 recycling to the plasma membrane and impacts the polar delivery of this transporter to the outer plasma membrane domain. This work establishes a functional link between the dynamics and the lateral polarity of IRT1 and the transport of its substrates, and identifies a molecular mechanism driving polar localization of a cell surface protein in plants.</dcterms:abstract> <dc:creator>Kolb, Cornelia</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-03-27T13:40:21Z</dcterms:available> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/38157"/> <dc:contributor>Isono, Erika</dc:contributor> <dcterms:title>Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis</dcterms:title> <dc:language>eng</dc:language> <dc:contributor>Barberon, Marie</dc:contributor> <dc:creator>Zelazny, Enric</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-03-27T13:40:21Z</dc:date> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/38157/3/Barberon_0-398682.pdf"/> <dc:contributor>Vert, Grégory</dc:contributor> <dc:contributor>Kolb, Cornelia</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:rights rdf:resource="http://nbn-resolving.de/urn:nbn:de:bsz:352-20150914100631302-4485392-8"/> <dcterms:issued>2014-06-03</dcterms:issued> <dc:creator>Barberon, Marie</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 27.03.2017 (Informationen über die Zugriffsstatistik)

Barberon_0-398682.pdf 11

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto