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Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries

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Prüfsumme: MD5:487295e1e743d8c792709646d2aa0014

STUETZ, Wolfgang, Daniela WEBER, Martijn DOLLÉ, Eugène JANSEN, Beatrix GRUBECK-LOEBENSTEIN, Simone FIEGL, Olivier TOUSSAINT, Juergen BERNHARDT, María MORENO-VILLANUEVA, Alexander BÜRKLE, 2016. Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries. In: Nutrients. 8(10), 614. eISSN 2072-6643

@article{Stuetz2016Plasm-37538, title={Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries}, year={2016}, doi={10.3390/nu8100614}, number={10}, volume={8}, journal={Nutrients}, author={Stuetz, Wolfgang and Weber, Daniela and Dollé, Martijn and Jansen, Eugène and Grubeck-Loebenstein, Beatrix and Fiegl, Simone and Toussaint, Olivier and Bernhardt, Juergen and Moreno-Villanueva, María and Bürkle, Alexander}, note={Article Number: 614} }

Jansen, Eugène Weber, Daniela Moreno-Villanueva, María Toussaint, Olivier 2017-02-17T08:05:19Z Grubeck-Loebenstein, Beatrix Bernhardt, Juergen Fiegl, Simone Dollé, Martijn Fiegl, Simone Bürkle, Alexander Moreno-Villanueva, María Bürkle, Alexander 2017-02-17T08:05:19Z Stuetz, Wolfgang Toussaint, Olivier Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels. Significant correlations with age were observed for lycopene (r = -0.248), α-tocopherol (r = 0.208), α-carotene (r = -0.112), and β-cryptoxanthin (r = 0.125; all p < 0.001). Age was inversely associated with lycopene (-6.5% per five-year age increase) and this association remained in the multiple regression model with the significant predictors (covariables) being country, season, cholesterol, gender, smoking status, body mass index (BMI (kg/m²)), and dietary habits. The positive association of α-tocopherol with age remained when all covariates including cholesterol and use of vitamin supplements were included (1.7% vs. 2.4% per five-year age increase). The association of higher β-cryptoxanthin with higher age was no longer statistically significant after adjustment for fruit consumption, whereas the inverse association of α-carotene with age remained in the fully adjusted multivariable model (-4.8% vs. -3.8% per five-year age increase). We conclude from our study that age is an independent predictor of plasma lycopene, α-tocopherol, and α-carotene. Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries eng Stuetz, Wolfgang Grubeck-Loebenstein, Beatrix Jansen, Eugène Bernhardt, Juergen Dollé, Martijn Weber, Daniela 2016

Dateiabrufe seit 17.02.2017 (Informationen über die Zugriffsstatistik)

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