Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

Shinde, Vaibhav; Perumal Srinivasan, Sureshkumar; Henry, Margit; Rotshteyn, Tamara; Hescheler, Jürgen; Rahnenführer, Jörg; Grinberg, Marianna; Meisig, Johannes; Blüthgen, Nils; Waldmann, Tanja; Leist, Marcel; Hengstler, Jan Georg; Sachinidis, Agapios

Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

Files

Shinde_0-386554.pdf(3.15 MB)

Date

2016

Authors

Shinde, Vaibhav

Perumal Srinivasan, Sureshkumar

Henry, Margit

Rotshteyn, Tamara

Hescheler, Jürgen

Rahnenführer, Jörg

Grinberg, Marianna

Meisig, Johannes

Blüthgen, Nils

Waldmann, Tanja

Show 3 more

EU project number

681002

Project

EUToxRisk21

Collections

Biologie

Publication type

Journal article

Publication status

Published

Published in

Stem cell research & therapy ; 7 (2016), 1. - 190. - eISSN 1757-6512

Abstract

Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the potential for human induced pluripotent stem cells (hiPSCs) to replace hESCs in such tests.

Subject (DDC)

570 Biosciences, Biology

Cite This

ISO 690

SHINDE, Vaibhav, Sureshkumar PERUMAL SRINIVASAN, Margit HENRY, Tamara ROTSHTEYN, Jürgen HESCHELER, Jörg RAHNENFÜHRER, Marianna GRINBERG, Johannes MEISIG, Nils BLÜTHGEN, Tanja WALDMANN, Marcel LEIST, Jan Georg HENGSTLER, Agapios SACHINIDIS, 2016. Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells. In: Stem cell research & therapy. 7(1), 190. eISSN 1757-6512. Available under: doi: 10.1186/s13287-016-0449-2

BibTex

@article{Shinde2016Compa-36720,
  year={2016},
  doi={10.1186/s13287-016-0449-2},
  title={Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells},
  number={1},
  volume={7},
  journal={Stem cell research & therapy},
  author={Shinde, Vaibhav and Perumal Srinivasan, Sureshkumar and Henry, Margit and Rotshteyn, Tamara and Hescheler, Jürgen and Rahnenführer, Jörg and Grinberg, Marianna and Meisig, Johannes and Blüthgen, Nils and Waldmann, Tanja and Leist, Marcel and Hengstler, Jan Georg and Sachinidis, Agapios},
  note={Article Number: 190}
}

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Bibliography of Konstanz

Yes