Modified Oligonucleotides as Tools for Allele-Specific Amplification

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STRERATH, Michael, Ilka DETMER, Jens GASTER, Andreas MARX, 2007. Modified Oligonucleotides as Tools for Allele-Specific Amplification. In: YURYEV, Anton, ed.. PCR Primer Design. Totowa, NJ:Humana Press, pp. 317-328. ISBN 978-1-58829-725-9

@incollection{Strerath2007Modif-33928, title={Modified Oligonucleotides as Tools for Allele-Specific Amplification}, year={2007}, doi={10.1007/978-1-59745-528-2_16}, number={402}, isbn={978-1-58829-725-9}, address={Totowa, NJ}, publisher={Humana Press}, series={Methods in Molecular Biology}, booktitle={PCR Primer Design}, pages={317--328}, editor={Yuryev, Anton}, author={Strerath, Michael and Detmer, Ilka and Gaster, Jens and Marx, Andreas} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/33928"> <dc:creator>Marx, Andreas</dc:creator> <dc:language>eng</dc:language> <dc:contributor>Strerath, Michael</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-05-13T09:52:08Z</dc:date> <dcterms:abstract xml:lang="eng">Allele-specific polymerase chain reaction (PCR), a method that reports nucleotide variations through either the presence or the absence of a DNA product obtained through PCR amplification, holds the promise to combine target amplification and analysis in one single step. Recently, it has been reported that the selectivity of allele-specific PCR can be significantly increased through the employment of chemically modified primer probes. Here, we report on significant developments of primer probe design and synthesis along this line.</dcterms:abstract> <dc:creator>Gaster, Jens</dc:creator> <dc:creator>Detmer, Ilka</dc:creator> <dcterms:issued>2007</dcterms:issued> <dcterms:title>Modified Oligonucleotides as Tools for Allele-Specific Amplification</dcterms:title> <dc:creator>Strerath, Michael</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-05-13T09:52:08Z</dcterms:available> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/33928"/> <dc:contributor>Detmer, Ilka</dc:contributor> <dc:contributor>Gaster, Jens</dc:contributor> <dc:contributor>Marx, Andreas</dc:contributor> </rdf:Description> </rdf:RDF>

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