The Cre/Lox System to Assess the Development of the Mouse Brain


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KRATOCHWIL, Claudius F., Filippo M. RIJLI, 2014. The Cre/Lox System to Assess the Development of the Mouse Brain. In: SPRECHER, Simon G, ed.. Brain Development : Methods and Protocols. Totowa, NJ:Humana Press, pp. 295-313. ISBN 978-1-62703-654-2. Available under: doi: 10.1007/978-1-62703-655-9_20

@incollection{Kratochwil2014CreLo-33372, title={The Cre/Lox System to Assess the Development of the Mouse Brain}, year={2014}, doi={10.1007/978-1-62703-655-9_20}, number={1082}, isbn={978-1-62703-654-2}, address={Totowa, NJ}, publisher={Humana Press}, series={Methods in Molecular Biology}, booktitle={Brain Development : Methods and Protocols}, pages={295--313}, editor={Sprecher, Simon G}, author={Kratochwil, Claudius F. and Rijli, Filippo M.} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dc:contributor>Rijli, Filippo M.</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Kratochwil, Claudius F.</dc:contributor> <dspace:isPartOfCollection rdf:resource=""/> <bibo:uri rdf:resource=""/> <dspace:isPartOfCollection rdf:resource=""/> <dcterms:isPartOf rdf:resource=""/> <dcterms:isPartOf rdf:resource=""/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Kratochwil, Claudius F.</dc:creator> <dc:language>eng</dc:language> <dcterms:available rdf:datatype="">2016-03-17T14:40:18Z</dcterms:available> <dc:creator>Rijli, Filippo M.</dc:creator> <dc:date rdf:datatype="">2016-03-17T14:40:18Z</dc:date> <dcterms:abstract xml:lang="eng">Cre-mediated recombination has become a powerful tool to confine gene deletions (conditional knockouts) or overexpression of genes (conditional knockin/overexpression). By spatiotemporal restriction of genetic manipulations, major problems of classical knockouts such as embryonic lethality can be circumvented. Furthermore Cre-mediated recombination has broad applicability in the analysis of the cellular behavior of subpopulations and cell types as well as for genetic fate mapping. This chapter will give an overview about applications for the Cre/LoxP system and their execution.</dcterms:abstract> <dcterms:issued>2014</dcterms:issued> <dcterms:title>The Cre/Lox System to Assess the Development of the Mouse Brain</dcterms:title> </rdf:Description> </rdf:RDF>

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