VisExpress : Visual exploration of differential gene expression data

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SIMON, Svenja, Sebastian MITTELSTÄDT, Bum Chul KWON, Andreas STOFFEL, Richard LANDSTORFER, Klaus NEUHAUS, Anna MÜHLIG, Siegfried SCHERER, Daniel A. KEIM, 2017. VisExpress : Visual exploration of differential gene expression data. In: Information Visualization. 16(1), pp. 48-73. ISSN 1473-8716. eISSN 1473-8724

@article{Simon2017-01VisEx-32512, title={VisExpress : Visual exploration of differential gene expression data}, year={2017}, doi={10.1177/1473871615612883}, number={1}, volume={16}, issn={1473-8716}, journal={Information Visualization}, pages={48--73}, author={Simon, Svenja and Mittelstädt, Sebastian and Kwon, Bum Chul and Stoffel, Andreas and Landstorfer, Richard and Neuhaus, Klaus and Mühlig, Anna and Scherer, Siegfried and Keim, Daniel A.} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/32512"> <dcterms:title>VisExpress : Visual exploration of differential gene expression data</dcterms:title> <dc:language>eng</dc:language> <dc:creator>Neuhaus, Klaus</dc:creator> <dc:contributor>Mühlig, Anna</dc:contributor> <dc:contributor>Mittelstädt, Sebastian</dc:contributor> <dc:creator>Simon, Svenja</dc:creator> <dc:creator>Scherer, Siegfried</dc:creator> <dc:contributor>Stoffel, Andreas</dc:contributor> <dcterms:rights rdf:resource="http://nbn-resolving.de/urn:nbn:de:bsz:352-20150914100631302-4485392-8"/> <dc:contributor>Neuhaus, Klaus</dc:contributor> <dc:creator>Kwon, Bum Chul</dc:creator> <dc:creator>Mittelstädt, Sebastian</dc:creator> <dc:contributor>Kwon, Bum Chul</dc:contributor> <dc:contributor>Simon, Svenja</dc:contributor> <dc:contributor>Landstorfer, Richard</dc:contributor> <dc:creator>Stoffel, Andreas</dc:creator> <dc:creator>Landstorfer, Richard</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-01-07T14:10:45Z</dcterms:available> <dc:creator>Mühlig, Anna</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-01-07T14:10:45Z</dc:date> <dc:contributor>Keim, Daniel A.</dc:contributor> <dcterms:abstract xml:lang="eng">Biologists are keen to understand how processes in cells react to environmental changes. Differential gene expression analysis allows biologists to explore functions of genes with data generated from different environments. However, these data and analysis lead to unique challenges since tasks are ill-defined, require implicit domain knowledge, comprise large volumes of data, and are, therefore, of explanatory nature. To investigate a scalable visualization-based solution, we conducted a design study with three biologists specialized in differential gene expression analysis. We stress our contributions in three aspects: first, we characterize the problem domain for exploring differential gene expression data and derive task abstractions and design requirements. Second, we investigate the design space and present an interactive visualization system, called VisExpress. Third, we evaluate the usefulness of VisExpress via a Pair Analytics study with real users and real data and report on insights that were gained by our experts with VisExpress.</dcterms:abstract> <dc:contributor>Scherer, Siegfried</dc:contributor> <dcterms:issued>2017-01</dcterms:issued> <dc:creator>Keim, Daniel A.</dc:creator> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/32512"/> </rdf:Description> </rdf:RDF>

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