Small-angle scattering as a tool to study the thermal denaturation of DNA

Zitieren

Dateien zu dieser Ressource

Dateien Größe Format Anzeige

Zu diesem Dokument gibt es keine Dateien.

WOOD, Kathleen, Robert KNOTT, Ognyan TONCHEV, Dimitar ANGELOV, Nikos THEODORAKOPOULOS, Michel PEYRARD, 2014. Small-angle scattering as a tool to study the thermal denaturation of DNA. In: EPL : Europhysics Letters. 108(1), 18002. ISSN 0295-5075. eISSN 1286-4854. Available under: doi: 10.1209/0295-5075/108/18002

@article{Wood2014Small-30027, title={Small-angle scattering as a tool to study the thermal denaturation of DNA}, year={2014}, doi={10.1209/0295-5075/108/18002}, number={1}, volume={108}, issn={0295-5075}, journal={EPL : Europhysics Letters}, author={Wood, Kathleen and Knott, Robert and Tonchev, Ognyan and Angelov, Dimitar and Theodorakopoulos, Nikos and Peyrard, Michel}, note={Article Number: 18002} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/30027"> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/30027"/> <dc:creator>Tonchev, Ognyan</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Theodorakopoulos, Nikos</dc:contributor> <dc:language>eng</dc:language> <dc:contributor>Angelov, Dimitar</dc:contributor> <dcterms:issued>2014</dcterms:issued> <dcterms:abstract xml:lang="eng">DNA thermal denaturation is the breaking of the base pairs, leading to a splitting of the two strands of the double helix. While it is easy to measure the fraction of open base pairs (f) vs. temperature, determining the fraction (p) of fully open molecules is much harder. Previously, the simultaneous recording of f and p could only be achieved for special sequences. We show that small-angle scattering of X-rays or neutrons allows the measurement of p for any sequence. We illustrate the method with a SAXS investigation of two sequences designed to exhibit different melting profiles and compare the SAXS data with nano-calorimetric measurements of the melting curve.</dcterms:abstract> <dc:contributor>Tonchev, Ognyan</dc:contributor> <dcterms:title>Small-angle scattering as a tool to study the thermal denaturation of DNA</dcterms:title> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2015-02-25T09:07:38Z</dc:date> <dc:creator>Theodorakopoulos, Nikos</dc:creator> <dc:creator>Knott, Robert</dc:creator> <dc:creator>Angelov, Dimitar</dc:creator> <dc:contributor>Knott, Robert</dc:contributor> <dc:creator>Peyrard, Michel</dc:creator> <dc:contributor>Wood, Kathleen</dc:contributor> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/41"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/41"/> <dc:creator>Wood, Kathleen</dc:creator> <dc:contributor>Peyrard, Michel</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2015-02-25T09:07:38Z</dcterms:available> </rdf:Description> </rdf:RDF>

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto