KOPS - The Institutional Repository of the University of Konstanz

Odor Discrimination in Drosophila : From Neural Population Codes to Behavior

Odor Discrimination in Drosophila : From Neural Population Codes to Behavior

Cite This

Files in this item

Checksum: MD5:19fbe0ae469c162851eff3de1eeb098a

PARNAS, Moshe, Andrew C. LIN, Wolf HUETTEROTH, Gero MIESENBÖCK, 2013. Odor Discrimination in Drosophila : From Neural Population Codes to Behavior. In: Neuron. 79(5), pp. 932-944. ISSN 0896-6273. eISSN 1097-4199. Available under: doi: 10.1016/j.neuron.2013.08.006

@article{Parnas2013-09-04Discr-28901, title={Odor Discrimination in Drosophila : From Neural Population Codes to Behavior}, year={2013}, doi={10.1016/j.neuron.2013.08.006}, number={5}, volume={79}, issn={0896-6273}, journal={Neuron}, pages={932--944}, author={Parnas, Moshe and Lin, Andrew C. and Huetteroth, Wolf and Miesenböck, Gero} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/28901"> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/28901/2/Parnas_289018.pdf"/> <dcterms:bibliographicCitation>Neuron ; 79 (2013), 5. - S. 932-944</dcterms:bibliographicCitation> <dc:language>eng</dc:language> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/28901/2/Parnas_289018.pdf"/> <dcterms:rights rdf:resource="https://kops.uni-konstanz.de/page/termsofuse"/> <dcterms:title>Odor Discrimination in Drosophila : From Neural Population Codes to Behavior</dcterms:title> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-09-05T11:28:58Z</dc:date> <dc:contributor>Miesenböck, Gero</dc:contributor> <dc:contributor>Huetteroth, Wolf</dc:contributor> <dc:contributor>Lin, Andrew C.</dc:contributor> <dcterms:abstract xml:lang="eng">Taking advantage of the well-characterized olfactory system of Drosophila, we derive a simple quantitative relationship between patterns of odorant receptor activation, the resulting internal representations of odors, and odor discrimination. Second-order excitatory and inhibitory projection neurons (ePNs and iPNs) convey olfactory information to the lateral horn, a brain region implicated in innate odor-driven behaviors. We show that the distance between ePN activity patterns is the main determinant of a fly's spontaneous discrimination behavior. Manipulations that silence subsets of ePNs have graded behavioral consequences, and effect sizes are predicted by changes in ePN distances. ePN distances predict only innate, not learned, behavior because the latter engages the mushroom body, which enables differentiated responses to even very similar odors. Inhibition from iPNs, which scales with olfactory stimulus strength, enhances innate discrimination of closely related odors, by imposing a high-pass filter on transmitter release from ePN terminals that increases the distance between odor representations.</dcterms:abstract> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/52"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:issued>2013-09-04</dcterms:issued> <dc:creator>Huetteroth, Wolf</dc:creator> <dc:contributor>Parnas, Moshe</dc:contributor> <dc:creator>Miesenböck, Gero</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/28901"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/52"/> <dc:creator>Lin, Andrew C.</dc:creator> <dc:rights>terms-of-use</dc:rights> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-09-05T11:28:58Z</dcterms:available> <dc:creator>Parnas, Moshe</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/28"/> </rdf:Description> </rdf:RDF>

Downloads since Oct 1, 2014 (Information about access statistics)

Parnas_289018.pdf 124

This item appears in the following Collection(s)

Search KOPS


Browse

My Account