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Ca<sup>2+</sup> regulation in the absence of the iplA gene product in Dictyostelium discoideum

Ca2+ regulation in the absence of the iplA gene product in Dictyostelium discoideum

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SCHALOSKE, Ralph H., Daniel F. LUSCHE, Karen BEZARES-RODER, Kathrin HAPPLE, Dieter MALCHOW, Christina SCHLATTERER, 2005. Ca2+ regulation in the absence of the iplA gene product in Dictyostelium discoideum. In: BMC Cell Biology. 6(1), 13. ISSN 1471-2121. eISSN 1471-2121. Available under: doi: 10.1186/1471-2121-6-13

@article{Schaloske2005regul-28165, title={Ca2+ regulation in the absence of the iplA gene product in Dictyostelium discoideum}, year={2005}, doi={10.1186/1471-2121-6-13}, number={1}, volume={6}, issn={1471-2121}, journal={BMC Cell Biology}, author={Schaloske, Ralph H. and Lusche, Daniel F. and Bezares-Roder, Karen and Happle, Kathrin and Malchow, Dieter and Schlatterer, Christina}, note={Article Number: 13} }

Lusche, Daniel F. 2005 Schlatterer, Christina eng Schaloske, Ralph H. Bezares-Roder, Karen Happle, Kathrin Stimulation of Dictyostelium discoideum with cAMP evokes an elevation of the cytosolic free Ca2+ concentration ([Ca2+]i). The [Ca2+]i-change is composed of liberation of stored Ca2+ and extracellular Ca2+-entry. The significance of the [Ca2+]i-transient for chemotaxis is under debate. Abolition of chemotactic orientation and migration by Ca2+-buffers in the cytosol indicates that a [Ca2+]i-increase is required for chemotaxis. Yet, the iplA- mutant disrupted in a gene bearing similarity to IP3-receptors of higher eukaryotes aggregates despite the absence of a cAMP-induced [Ca2+]i-transient which favours the view that [Ca2+]i-changes are insignificant for chemotaxis. Schaloske, Ralph H. Malchow, Dieter Schlatterer, Christina deposit-license Ca<sup>2+</sup> regulation in the absence of the iplA gene product in Dictyostelium discoideum Bezares-Roder, Karen Lusche, Daniel F. 2014-07-23T06:52:25Z BMC Cell Biology ; 6 (2005). - 13 2014-07-23T06:52:25Z Happle, Kathrin Malchow, Dieter

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

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