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Signaling by epithelial members of the CEACAM Family - mucosal docking sites for pathogenic bacteria

Signaling by epithelial members of the CEACAM Family - mucosal docking sites for pathogenic bacteria

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KENGMO TCHOUPA, Arnaud, Tamara SCHUHMACHER, Christof R. HAUCK, 2014. Signaling by epithelial members of the CEACAM Family - mucosal docking sites for pathogenic bacteria. In: Cell Communication and Signaling. 12(1), 27. eISSN 1478-811X

@article{Kengmo Tchoupa2014Signa-28077, title={Signaling by epithelial members of the CEACAM Family - mucosal docking sites for pathogenic bacteria}, year={2014}, doi={10.1186/1478-811X-12-27}, number={1}, volume={12}, journal={Cell Communication and Signaling}, author={Kengmo Tchoupa, Arnaud and Schuhmacher, Tamara and Hauck, Christof R.}, note={Article Number: 27} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/28077"> <dc:rights>deposit-license</dc:rights> <dcterms:bibliographicCitation>Cell Communication and Signaling ; 12 (2014). - 27</dcterms:bibliographicCitation> <dc:language>eng</dc:language> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-06-24T09:04:45Z</dc:date> <dcterms:abstract xml:lang="eng">Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a group of immunoglobulin-related vertebrate glycoproteins. Several family members, including CEACAM1, CEA, and CEACAM6, are found on epithelial tissues throughout the human body. As they modulate diverse cellular functions, their signaling capacity is in the focus of current research. In this review we will summarize the knowledge about common signaling processes initiated by epithelial CEACAMs and suggest a model of signal transduction by CEACAM family members lacking significant cytoplasmic domains. As pathogenic and non-pathogenic bacteria exploit these receptors during mucosal colonization, we try to highlight the connection between CEACAMs, microbes, and cellular responses. Special emphasis in this context is placed on the functional interplay between CEACAMs and integrins that influences matrix adhesion of epithelial cells. The cooperation between these two receptor families provides an intriguing example of the fine tuning of cellular responses and their manipulation by specialized microorganisms.</dcterms:abstract> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/28077"/> <dc:creator>Kengmo Tchoupa, Arnaud</dc:creator> <dc:creator>Schuhmacher, Tamara</dc:creator> <dc:contributor>Hauck, Christof R.</dc:contributor> <dc:contributor>Schuhmacher, Tamara</dc:contributor> <dc:creator>Hauck, Christof R.</dc:creator> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> <dcterms:issued>2014</dcterms:issued> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-06-24T09:04:45Z</dcterms:available> <dc:contributor>Kengmo Tchoupa, Arnaud</dc:contributor> <dcterms:title>Signaling by epithelial members of the CEACAM Family - mucosal docking sites for pathogenic bacteria</dcterms:title> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

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