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Display of 10 of 29 results for the collection: Biologie.

Now showing items 1-10 of 29

(3.6 MiB)

Examination of microcystin neurotoxicity using central and peripheral human neurons

Klima, Stefanie; Suciu, Ilinca; Hoelting, Lisa; Gutbier, Simon; Waldmann, Tanja; Dietrich, Daniel R.; Leist, Marcel (2021) - Journal article
Published in: Alternatives to Animal Experimentation : ALTEX ; 38 (2021), 1. - pp. 73-81. - Springer Spektrum. - ISSN 1868-596X. - eISSN 1868-8551
(3 MiB)

Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

Meisig, Johannes; Dreser, Nadine; Kapitza, Marion; Henry, Margit; Rotshteyn, Tamara; Rahnenführer, Jörg; Hengstler, Jan G; Waldmann, Tanja; Leist, Marcel; Blüthgen, Nils et al. (2020) - Journal article
Published in: Nucleic Acids Research ; 48 (2020), 22. - pp. 12577-12592. - Oxford University Press. - ISSN 0305-1048. - eISSN 1362-4962
(4.8 MiB)

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

Krebs, Alice; van Vugt-Lussenburg, Barbara M. A.; Waldmann, Tanja; Busquet, Francois; Dolde, Xenia; Holzer, Anna-Katharina; Kisitu, Jaffar; Pallocca, Giorgia; Rovida, Costanza; Leist, Marcel et al. (2020) - Journal article
Published in: Archives of Toxicology ; 94 (2020), 7. - pp. 2435-2461. - Springer. - ISSN 0340-5761. - eISSN 1432-0738
(3.5 MiB)

Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances

Dreser, Nadine; Holzer, Anna-Katharina; Kapitza, Marion; Scholz, Christopher; Kranaster, Petra; Gutbier, Simon; Klima, Stefanie; Kolb, David; Dietz, Christian; Trefzer, Timo; Berthold, Michael R.; Waldmann, Tanja; Leist, Marcel et al. (2020) - Journal article
Published in: Archives of Toxicology ; 94 (2020), 1. - pp. 151-171. - Springer Science and Business Media. - ISSN 0340-5761. - eISSN 1432-0738
(1.1 MiB)

Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data

Krebs, Alice; Waldmann, Tanja; Rovida, Costanza; Pallocca, Giorgia; Hartung, Thomas; Gantner, Florian; Exner, Thomas; Dietrich, Daniel R.; Busquet, Francois; Leist, Marcel et al. (2019) - Journal article
Published in: Alternatives to Animal Experimentation : ALTEX ; 36 (2019), 4. - pp. 682-699. - ISSN 1868-596X. - eISSN 1868-8551
(9.2 MiB)

Major changes of cell function and toxicant sensitivity in cultured cells undergoing mild, quasi-natural genetic drift

Gutbier, Simon; May, Patrick; Berthelot, Sylvie; Krishna, Abhimanyu; Trefzer, Timo; Behbehani, Mehri; Efremova, Liudmila; Delp, Johannes; Gstraunthaler, Gerhard; Waldmann, Tanja; Leist, Marcel (2018) - Journal article
Published in: Archives of Toxicology ; 92 (2018), 12. - pp. 3487-3503. - ISSN 0340-5761. - eISSN 1432-0738
(1.3 MiB)

Stage-specific metabolic features of differentiating neurons : Implications for toxicant sensitivity

Delp, Johannes; Gutbier, Simon; Cerff, Martin; Hartung, Thomas; Borlinghaus, Hanna; Schreiber, Falk; Waldmann, Tanja; Kempa, Stefan; Nöh, Katharina; Leist, Marcel et al. (2018) - Journal article
Published in: Toxicology and Applied Pharmacology ; 354 (2018). - pp. 64-80. - ISSN 0041-008X. - eISSN 1096-0333
(6.1 MiB)

Recommendation on test readiness criteria for new approach methods in toxicology : Exemplified for developmental neurotoxicity

Bal-Price, Anna K.; Hogberg, Helena T.; Crofton, Kevin M.; Daneshian, Mardas; FitzGerald, Rex E.; Fritsche, Ellen; Heinonen, Tuula; Klima, Stefanie; Waldmann, Tanja; Leist, Marcel et al. (2018) - Journal article
Published in: Alternatives to Animal Experimentation : ALTEX ; 35 (2018), 3. - pp. 306-352. - ISSN 1868-596X. - eISSN 1868-8551
(783.4 KiB)

Adverse outcome pathways : opportunities, limitations and open questions

Leist, Marcel; Ghallab, Ahmed; Graepel, Rabea; Marchan, Rosemarie; Hassan, Reham; Bennekou, Susanne Hougaard; Schildknecht, Stefan; Waldmann, Tanja; Hartung, Thomas; Hengstler, Jan G. et al. (2017) - Journal article
Published in: Archives of toxicology ; 91 (2017), 11. - pp. 3477-3505. - ISSN 0340-5761. - eISSN 1432-0738
(1.5 MiB)

Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library

Nyffeler, Johanna; Dolde, Xenia; Krebs, Alice; Pinto-Gil, Kevin; Pastor, Manuel; Behl, Mamta; Waldmann, Tanja; Leist, Marcel (2017) - Journal article
Published in: Archives of Toxicology ; 91 (2017), 11. - pp. 3613-3632. - ISSN 0340-5761. - eISSN 1432-0738

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