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Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans

Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans

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IMTHURN, Bruno, Marinella ROSSELLI, Jan BERAN, Paul J. KELLER, 1995. Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans. In: Hormone and Metabolic Research. 27(04), pp. 189-193. ISSN 0018-5043. eISSN 1439-4286. Available under: doi: 10.1055/s-2007-979937

@article{Imthurn1995-04Evide-27481, title={Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans}, year={1995}, doi={10.1055/s-2007-979937}, number={04}, volume={27}, issn={0018-5043}, journal={Hormone and Metabolic Research}, pages={189--193}, author={Imthurn, Bruno and Rosselli, Marinella and Beran, Jan and Keller, Paul J.} }

Keller, Paul J. Imthurn, Bruno Rosselli, Marinella 2014-04-07T09:32:43Z 2014-04-07T09:32:43Z Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans Beran, Jan Hormone and Metabolic Research ; 27 (1995), 4. - S. 189-193 Imthurn, Bruno deposit-license eng Rosselli, Marinella Keller, Paul J. Objective<br />To investigate whether high-frequency periodic fluctuation in the release of plasma immunoreactive (ir)-beta-endorphin occurs in humans. Design, patients and measurements: Blood was collected at 90-sec intervals for 1 hour from the forearm vein of four healthy women and subsequently analysed for ir-beta-endorphin by radioimmunoassay.<br /><br />Results<br />In all women circulating beta-endorphin release followed a high-frequency periodic rhythm pattern. The estimated spectral densities within the four subjects varied between 3.6 min to 4.9 min.<br /><br />Conclusions<br />Our results provide the first in vivo evidence that fluctuations in the release of beta-endorphin in humans cannot only be characterized by low-frequency pulses, but also by a high frequency periodic rhythm. Beran, Jan 1995-04

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