Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host - parasite interactions

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2013
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BMC Ecology. 2013, 13(1), 41. eISSN 1472-6785. Available under: doi: 10.1186/1472-6785-13-41
Zusammenfassung

Background

Interactions between hosts and parasites can be substantially modulated by host nutrition.
Polyunsaturated fatty acids (PUFAs) are essential dietary nutrients; they are indispensable as structural components
of cell membranes and as precursors for eicosanoids, signalling molecules which act on reproduction and
immunity. Here, we explored the potential of dietary PUFAs to affect the course of parasitic infections using a
well-established invertebrate host – parasite system, the freshwater herbivore Daphnia magna and its bacterial
parasite Pasteuria ramosa.


Results

Using natural food sources differing in their PUFA composition and by experimentally modifying the
availability of dietary arachidonic acid (ARA) and eicosapentaenoic acid (EPA) we examined PUFA-mediated effects
resulting from direct consumption as well as maternal effects on offspring of treated mothers. We found that both
host and parasite were affected by food quality. Feeding on C20 PUFA-containing food sources resulted in higher
offspring production of hosts and these effects were conveyed to a great extent to the next generation. While
feeding on a diet containing high PUFA concentrations significantly reduced the likelihood of becoming infected,
the infection success in the next generation increased whenever the maternal diet contained PUFAs. We suggest
that this opposing effect was caused by a trade-off between reproduction and immunity in the second generation.


Conclusions

Considering the direct and maternal effects of dietary PUFAs on host and parasite we propose that
host – parasite interactions and thus disease dynamics under natural conditions are subject to the availability of
dietary PUFAs.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Arachidonic acid, Daphnia magna, Eicosapentaenoic acid, Food quality, Host parasite interactions, Immunity, Nutrition, Pasteuria ramosa, Resistance
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ISO 690SCHLOTZ, Nina, Dieter EBERT, Dominik MARTIN-CREUZBURG, 2013. Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host - parasite interactions. In: BMC Ecology. 2013, 13(1), 41. eISSN 1472-6785. Available under: doi: 10.1186/1472-6785-13-41
BibTex
@article{Schlotz2013Dieta-25980,
  year={2013},
  doi={10.1186/1472-6785-13-41},
  title={Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host - parasite interactions},
  number={1},
  volume={13},
  journal={BMC Ecology},
  author={Schlotz, Nina and Ebert, Dieter and Martin-Creuzburg, Dominik},
  note={Article Number: 41}
}
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