Endophenotypes in psychopathology research : Where do we stand?

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MILLER, Gregory A., Brigitte ROCKSTROH, 2013. Endophenotypes in psychopathology research : Where do we stand?. In: Annual Review of Clinical Psychology. 9(1), pp. 177-213. ISSN 1548-5943. eISSN 1548-5951

@article{Miller2013Endop-23060, title={Endophenotypes in psychopathology research : Where do we stand?}, year={2013}, doi={10.1146/annurev-clinpsy-050212-185540}, number={1}, volume={9}, issn={1548-5943}, journal={Annual Review of Clinical Psychology}, pages={177--213}, author={Miller, Gregory A. and Rockstroh, Brigitte} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/23060"> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/23060"/> <dc:language>eng</dc:language> <dc:contributor>Miller, Gregory A.</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-05-16T10:12:16Z</dc:date> <dc:contributor>Rockstroh, Brigitte</dc:contributor> <dcterms:abstract xml:lang="eng">Endophenotypes for psychopathology have beenn conceived as latent, unobserved, but measureable manifestations of phenomena that causally connect genetic liability to clinical disorder. Several decades of research have led to refinement of the construct and identification of some candidate endophenotypes, but rather limited progress on finding the genes involved or the mechanisms by which endophenotypes are driven by genetic and environmental factors and in turn drive psychopathology. Currently promising avenues for research involve development of transdiagnostic concepts not limited to traditional diagnostic categories, measures of endophenotypic and manifest psychopathology that have higher validity than those categories, and methods for modeling complex relationships among diverse contributors to etiology. With more grounding in animal neuroscience and other aspects of basic biological and psychological science, exemplified in the Research Domain Criteria initiative, there is every reason to anticipate that the endophenotype concept will grow more central in the psychopathology literature.</dcterms:abstract> <dc:creator>Miller, Gregory A.</dc:creator> <dc:rights>deposit-license</dc:rights> <dcterms:bibliographicCitation>Annual Review of Clinical Psychology ; 9 (2013). - S. 177-213</dcterms:bibliographicCitation> <dcterms:issued>2013</dcterms:issued> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-05-16T10:12:16Z</dcterms:available> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> <dcterms:title>Endophenotypes in psychopathology research : Where do we stand?</dcterms:title> <dc:creator>Rockstroh, Brigitte</dc:creator> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

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