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Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing : initial experience

Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing : initial experience

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Prüfsumme: MD5:cd6b543a431df2e178edda40a5ff9d38

KUHNT, Daniela, Miriam H. A. BAUER, Jan EGGER, Mirco RICHTER, Tina KAPUR, Jens SOMMER, Dorit MERHOF, Christopher NIMSKY, 2013. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing : initial experience. In: Neurosurgery. 73(5), pp. E913-A175. ISSN 0148-396X. eISSN 1524-4040

@article{Kuhnt2013-01Fiber-22428, title={Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing : initial experience}, year={2013}, doi={10.1227/NEU.0b013e318270d9fb}, number={5}, volume={73}, issn={0148-396X}, journal={Neurosurgery}, pages={E913--A175}, author={Kuhnt, Daniela and Bauer, Miriam H. A. and Egger, Jan and Richter, Mirco and Kapur, Tina and Sommer, Jens and Merhof, Dorit and Nimsky, Christopher} }

Kuhnt, Daniela Kuhnt, Daniela Richter, Mirco 2013-01 deposit-license Sommer, Jens Egger, Jan Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing : initial experience Nimsky, Christopher 2014-01-14T23:25:07Z eng 2013-04-10T09:38:11Z Merhof, Dorit Egger, Jan Bauer, Miriam H. A. Richter, Mirco Background:<br /><br /><br />The most frequently used method for fiber tractography based on diffusion tensor imaging (DTI) is associated with restrictions in the resolution of crossing or kissing fibers and in the vicinity of tumor or edema. Tractography based on high-angular-resolution diffusion imaging (HARDI) is capable of overcoming this restriction. With compressed sensing (CS) techniques, HARDI acquisitions with a smaller number of directional measurements can be used, thus enabling the use of HARDI-based fiber tractography in clinical practice.<br /><br /><br />Objective:<br /><br /><br />To investigate whether HARDI+CS-based fiber tractography improves the display of neuroanatomically complex pathways and in areas of disturbed diffusion properties.<br /><br /><br />Methods:<br /><br />Six patients with gliomas in the vicinity of language-related areas underwent 3-T magnetic resonance imaging including a diffusion-weighted data set with 30 gradient directions. Additionally, functional magnetic resonance imaging for cortical language sites was obtained. Fiber tractography was performed with deterministic streamline algorithms based on DTI using 3 different software platforms. Additionally, tractography based on reconstructed diffusion signals using HARDI+CS was performed.<br /><br /><br />Results:<br /><br /><br />HARDI+CS-based tractography displayed more compact fiber bundles compared with the DTI-based results in all cases. In 3 cases, neuroanatomically plausible fiber bundles were displayed in the vicinity of tumor and peritumoral edema, which could not be traced on the basis of DTI. The curvature around the sylvian fissure was displayed properly in 6 cases and in only 2 cases with DTI-based tractography.<br /><br /><br />Conclusion:<br /><br /><br />HARDI+CS seems to be a promising approach for fiber tractography in clinical practice for neuroanatomically complex fiber pathways and in areas of disturbed diffusion, overcoming the problem of long acquisition times. Kapur, Tina Bauer, Miriam H. A. Kapur, Tina Nimsky, Christopher Sommer, Jens Merhof, Dorit Neurosurgery ; 72 (2013), Suppl. 1. - S. A165-A175

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

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