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Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs

Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs

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CURTIS, Bruce A., Goro TANIFUJI, Fabien BURKI, Ansgar GRUBER, Peter G. KROTH, 2012. Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. In: Nature. 492(7427), pp. 59-65. ISSN 0028-0836. eISSN 1476-4687. Available under: doi: 10.1038/nature11681

@article{Curtis2012-12-06Algal-22151, title={Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs}, year={2012}, doi={10.1038/nature11681}, number={7427}, volume={492}, issn={0028-0836}, journal={Nature}, pages={59--65}, author={Curtis, Bruce A. and Tanifuji, Goro and Burki, Fabien and Gruber, Ansgar and Kroth, Peter G.}, note={Aufgrund einer zu hohen Autorenanzahl, können hier nicht alle Autoren aufgezählt werden. Im pdf sind alle Autoren genannt.} }

Gruber, Ansgar Gruber, Ansgar Tanifuji, Goro Kroth, Peter G. Curtis, Bruce A. Tanifuji, Goro 2013-03-06T10:41:26Z Cryptophyte and chlorarachniophyte algae are transitional forms in the widespread secondary endosymbiotic acquisition of photosynthesis by engulfment of eukaryotic algae. Unlike most secondary plastid-bearing algae, miniaturized versions of the endosymbiont nuclei (nucleomorphs) persist in cryptophytes and chlorarachniophytes. To determine why, and to address other fundamental questions about eukaryote-eukaryote endosymbiosis, we sequenced the nuclear genomes of the cryptophyte Guillardia theta and the chlorarachniophyte Bigelowiella natans. Both genomes have >21,000 protein genes and are intron rich, and B. natans exhibits unprecedented alternative splicing for a single-celled organism. Phylogenomic analyses and subcellular targeting predictions reveal extensive genetic and biochemical mosaicism, with both host- and endosymbiont-derived genes servicing the mitochondrion, the host cell cytosol, the plastid and the remnant endosymbiont cytosol of both algae. Mitochondrion-to-nucleus gene transfer still occurs in both organisms but plastid-to-nucleus and nucleomorph-to-nucleus transfers do not, which explains why a small residue of essential genes remains locked in each nucleomorph. Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs eng Kroth, Peter G. Burki, Fabien Burki, Fabien terms-of-use Curtis, Bruce A. 2013-03-06T10:41:26Z 2012-12-06 Nature ; 492 (2012), 7427. - S. 59-65

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