Synthesis and stability of phosphate modified ATP analogues

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HACKER, Stephan, Martin MEX, Andreas MARX, 2012. Synthesis and stability of phosphate modified ATP analogues. In: The Journal of Organic Chemistry. 77(22), pp. 10450-10454. ISSN 0022-3263. eISSN 1520-6904. Available under: doi: 10.1021/jo301923p

@article{Hacker2012-11-16Synth-20908, title={Synthesis and stability of phosphate modified ATP analogues}, year={2012}, doi={10.1021/jo301923p}, number={22}, volume={77}, issn={0022-3263}, journal={The Journal of Organic Chemistry}, pages={10450--10454}, author={Hacker, Stephan and Mex, Martin and Marx, Andreas} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dc:contributor>Hacker, Stephan</dc:contributor> <dc:creator>Marx, Andreas</dc:creator> <dcterms:available rdf:datatype="">2012-11-28T09:44:58Z</dcterms:available> <dcterms:rights rdf:resource=""/> <dcterms:issued>2012-11-16</dcterms:issued> <dc:language>eng</dc:language> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Mex, Martin</dc:creator> <bibo:uri rdf:resource=""/> <dcterms:isPartOf rdf:resource=""/> <dcterms:title>Synthesis and stability of phosphate modified ATP analogues</dcterms:title> <dc:rights>terms-of-use</dc:rights> <dcterms:abstract xml:lang="eng">Nucleotides modified at the phosphate have numerous applications. Nevertheless, the number of attachment modes is limited and little is known about their stability. Here, we present results on the elaboration of the synthesis of five classes of ATP analogues and studies concerning their stability. We show that the nitrogen-linked ATP analogue is less stable, whereas the oxygen- and novel carbon-linked adenosine tri- and tetraphosphate analogues are stable from pH 3 to 12 rendering them interesting for further applications and designs.</dcterms:abstract> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Marx, Andreas</dc:contributor> <dc:date rdf:datatype="">2012-11-28T09:44:58Z</dc:date> <dcterms:bibliographicCitation>Journal of Organic Chemistry ; 77 (2012), 22. - S. 10450–10454</dcterms:bibliographicCitation> <dspace:isPartOfCollection rdf:resource=""/> <dc:creator>Hacker, Stephan</dc:creator> <dc:contributor>Mex, Martin</dc:contributor> </rdf:Description> </rdf:RDF>

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