KOPS - Das Institutionelle Repositorium der Universität Konstanz

Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens

Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:f292e140e29677b4511ef173d65a5a57

GARGIULO, Pascual A., Martina SIEMANN, Juan DELIUS, 1998. Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens. In: Physiology & Behavior. 63(4), pp. 705-709. ISSN 0031-9384. Available under: doi: 10.1016/S0031-9384(97)00516-7

@article{Gargiulo1998Visua-20492, title={Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens}, year={1998}, doi={10.1016/S0031-9384(97)00516-7}, number={4}, volume={63}, issn={0031-9384}, journal={Physiology & Behavior}, pages={705--709}, author={Gargiulo, Pascual A. and Siemann, Martina and Delius, Juan} }

The nucleus accumbens septi (Acc) is thought to be involved in the control of cognitive processes and to be implicated in the pathophysiology of schizophrenia. Because perceptual-cognitive distortions are a core symptom in schizophrenia, any evidence that the Acc intervenes in a sensory recognition task in an animal species would be of interest. Pigeons were instrumentally trained to discriminate visual shapes. The acute effects of drug microinjections into the Acc on the discrimination of the training shapes, on the correction responding after errors, and on the generalisation to different shapes were examined. The effects of conduction blockade with lidocaine, glutamatergic blockade with 7-aminophosphonoheptanoic acid, and dopaminergic stimulation with apomorphine on behavioural performance were tested. No effects were observed with lidocaine and apomorphine. A significant and reversible performance disruption to near chance levels was obtained after aminophosphonoheptanoic acid injections into the Acc. It appears that a glutamatergic blockade of the Acc interferes with the visual discrimination processes of pigeons. Siemann, Martina eng Gargiulo, Pascual A. 1998 Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens 2012-10-10T09:45:05Z 2012-10-10T09:45:05Z Delius, Juan Delius, Juan Gargiulo, Pascual A. Physiology & Behavior ; 63 (1998), 4. - S. 705-709 deposit-license Siemann, Martina

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

Delius Visual discrimination.pdf 189

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto