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Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci

Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci

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MERHOF, Dorit, Christian MATHERS, Thomas WRIGHT, Torsten KUWERT, Günther PLATSCH, 2010. Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci. 2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC). Knoxville, TN, 30. Okt 2010 - 6. Nov 2010. In: IEEE Nuclear Science Symposuim & Medical Imaging Conference. 2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC). Knoxville, TN, 30. Okt 2010 - 6. Nov 2010. IEEE, pp. 2338-2341. ISBN 978-1-4244-9106-3

@inproceedings{Merhof2010-10Analy-18653, title={Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci}, year={2010}, doi={10.1109/NSSMIC.2010.5874202}, isbn={978-1-4244-9106-3}, publisher={IEEE}, booktitle={IEEE Nuclear Science Symposuim & Medical Imaging Conference}, pages={2338--2341}, author={Merhof, Dorit and Mathers, Christian and Wright, Thomas and Kuwert, Torsten and Platsch, Günther} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/18653"> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/18653"/> <dc:creator>Merhof, Dorit</dc:creator> <dc:creator>Mathers, Christian</dc:creator> <dc:contributor>Kuwert, Torsten</dc:contributor> <dc:rights>deposit-license</dc:rights> <dc:contributor>Wright, Thomas</dc:contributor> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> <dc:contributor>Merhof, Dorit</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-03-20T10:11:02Z</dcterms:available> <dc:creator>Platsch, Günther</dc:creator> <dcterms:title>Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci</dcterms:title> <dc:language>eng</dc:language> <dcterms:bibliographicCitation>First publ. in: 2010 IEEE Nuclear Science Symposium conference record (NSS/MIC 2010) : [including the 2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, and the 17th International Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors (RTSD)] ; Knoxville, Tennessee, USA, 30 October - 6 November 2010 / [sponsored by the Nuclear and Plasma Sciences Society of the Institute of Electrical and Electronic Engineers ...]. - Piscataway, NJ : IEEE, 2010. - S. 2338 - 2341. - ISBN 978-1-424-49106-3</dcterms:bibliographicCitation> <dcterms:abstract xml:lang="eng">In patients suffering from focal epilepsy, the region of seizure onset is characterized by hyperperfusion during the seizure (ictal state), and hypoperfusion in normal (inter-ictal) state. For diagnosis and surgery planning in epilepsy patients, ictal and inter-ictal SPECT images play a major role. However, comparison of this kind of data is a difficult clinical problem due to varying physiological uptake in brain regions. For this reason, different analysis methods such as standard reading by a clinical expert, comparison to a normal database, subtraction ictal SPECT co-registered to MRI (SISCOM) or asymmetry analysis are applied, for a comprehensive analysis of the data. The latter is usually hampered by functional and anatomical asymmetries which aggravate analysis. For this reason, a novel approach for asymmetry analysis is presented in this work, which overcomes the aforementioned limitations. The approach was successfully applied to SPECT datasets of 10 epilepsy patients.</dcterms:abstract> <dc:contributor>Mathers, Christian</dc:contributor> <dc:creator>Kuwert, Torsten</dc:creator> <dc:creator>Wright, Thomas</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-03-20T10:11:02Z</dc:date> <dc:contributor>Platsch, Günther</dc:contributor> <dcterms:issued>2010-10</dcterms:issued> </rdf:Description> </rdf:RDF>

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